Wagner Felix Mathias, Oster Paul, Stingl Julia Veran, Schuster Alexander Karl-Georg, Rezapour Jasmin, Mendoza-Moreira Angi Liz, Fieß Achim, Messerschmidt-Roth Anke, Grehn Franz, Pfeiffer Norbert, Hoffmann Esther Maria
Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Ophthalmology Department, Philipps University of Marburg, 35043 Marburg, Germany.
J Clin Med. 2024 Dec 2;13(23):7341. doi: 10.3390/jcm13237341.
: This study aims to compare the effectiveness of traditional rigid probe trabeculotomy and 360-degree catheter trabeculotomy in treating childhood glaucoma, underlining the necessity of early surgical intervention. This retrospective cohort study, conducted at the University Eye Hospital Mainz, Germany, included 109 patients under 18 years with childhood glaucoma who underwent rigid probe trabeculotomy or 360-degree catheter trabeculotomy between January 2015 and February 2021. A total of 151 eyes from 109 patients were included. The average IOP decreased significantly in both groups, with a greater reduction seen in the 360-degree catheter trabeculotomy group (mean reduction: 10.1 ± 8.7 mmHg; < 0.001). In the rigid probe trabeculotomy group, the IOP reduction was 8.1 ± 9.0 mmHg ( < 0.001). The need for revision surgeries was lower in the 360-degree catheter trabeculotomy group. Both trabeculotomy techniques effectively reduced the intraocular pressure in childhood glaucoma. The 360-degree catheter trabeculotomy group demonstrated fewer revision surgeries compared to the rigid probe trabeculotomy group. However, there was no statistically significant difference in the IOP reduction between the groups. These findings indicate that while both methods are effective in managing the IOP in childhood glaucoma, the 360-degree catheter trabeculotomy may provide more favorable long-term results.
本研究旨在比较传统硬性探针小梁切开术与360度导管小梁切开术治疗儿童青光眼的有效性，强调早期手术干预的必要性。这项回顾性队列研究在德国美因茨大学眼科医院进行，纳入了109例18岁以下患有儿童青光眼的患者，这些患者在2015年1月至2021年2月期间接受了硬性探针小梁切开术或360度导管小梁切开术。共纳入了109例患者的151只眼睛。两组患者的平均眼压均显著降低，360度导管小梁切开术组降低幅度更大（平均降低：10.1±8.7 mmHg；<0.001）。在硬性探针小梁切开术组中，眼压降低了8.1±9.0 mmHg（<0.001）。360度导管小梁切开术组翻修手术的需求较低。两种小梁切开术技术均能有效降低儿童青光眼的眼压。与硬性探针小梁切开术组相比，360度导管小梁切开术组的翻修手术较少。然而，两组之间眼压降低幅度没有统计学上的显著差异。这些发现表明，虽然两种方法在控制儿童青光眼眼压方面均有效，但360度导管小梁切开术可能会提供更有利的长期效果。
