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用于盆腔器官脱垂手术治疗的G型网片妇科网片的安全性和有效性——一项回顾性分析

Safety and Effectiveness of G-Mesh Gynecological Meshes Intended for Surgical Treatment of Pelvic Organ Prolapse-A Retrospective Analysis.

作者信息

Wilczak Maciej, Chmaj-Wierzchowska Karolina, Wójtowicz Mariusz, Kądziołka Przemysław, Paul Paulina, Gajdzicka Aleksandra, Jezierska Kaja, Sujka Witold

机构信息

Department of Maternal and Child Health and Minimally Invasive Surgery, Poznan University of Medical Sciences, 60-701 Poznan, Poland.

Municipal Hospital in Zabrze, Zamkowa 4, 41-803 Zabrze, Poland.

出版信息

J Clin Med. 2024 Dec 5;13(23):7421. doi: 10.3390/jcm13237421.

Abstract

The prevalence of POP in women ranges from 30-40%, with 10-20% requiring surgical intervention. Annually, over 225,000 surgical procedures for POP are performed in the United States. The severity of prolapse is assessed using the four-stage POP-Q system, which facilitates clinical research by providing a standardized measure of defect severity. Surgical intervention is indicated for more severe cases, with various techniques available through vaginal or abdominal access. Synthetic meshes, primarily made of polypropylene (PP), are commonly used in POP surgeries due to their biocompatibility and mechanical support. This research aims to evaluate the effectiveness and safety of a non-resorbable, light polypropylene gynecological mesh (G-Mesh, Tricomed S.A., Łódź, Poland) in the surgical treatment of pelvic floor prolapse in women. The meshes were implanted via laparoscopy (Dubuisson method) and laparotomy or transvaginally. A multicenter, retrospective study was conducted involving 81 patients aged 28-83. The results collected at three follow-up visits indicated a high level of patient satisfaction, minimal discomfort, and no significant pain. Many patients emphasized significant improvement in quality of life and the lack of any adverse events associated with the presence of the implant. The G-Mesh gynecological mesh has emerged as an effective and safe intervention for treating pelvic floor dysfunction in women, addressing conditions such as cystocele, rectocele, uterine prolapse, and ureterocele.

摘要

女性盆腔器官脱垂(POP)的患病率在30%-40%之间,其中10%-20%需要手术干预。在美国,每年进行超过22.5万例POP手术。脱垂的严重程度使用四阶段POP-Q系统进行评估,该系统通过提供缺陷严重程度的标准化测量来促进临床研究。对于更严重的病例,需要进行手术干预,可通过阴道或腹部途径采用各种技术。合成网片主要由聚丙烯(PP)制成,因其生物相容性和机械支撑性,常用于POP手术。本研究旨在评估一种不可吸收的轻质聚丙烯妇科网片(G-Mesh,Tricomed S.A.,波兰罗兹)在女性盆底脱垂手术治疗中的有效性和安全性。这些网片通过腹腔镜(杜布瓦松法)、剖腹术或经阴道植入。进行了一项多中心回顾性研究,涉及81名年龄在28-83岁之间的患者。在三次随访中收集的结果表明患者满意度高、不适最小且无明显疼痛。许多患者强调生活质量有显著改善,且未出现与植入物相关的任何不良事件。G-Mesh妇科网片已成为治疗女性盆底功能障碍的一种有效且安全的干预措施,可治疗膀胱膨出、直肠膨出、子宫脱垂和输尿管膨出等病症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f0b/11642310/38cc0275701b/jcm-13-07421-g001.jpg

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