Xu Wen, Lv Yang, Zhu Ying, Zhang Yingchun, Gong Wei, Cui Xiaobing
Department of Gastroenterology, Shenzhen Hospital of Southern Medical University, Shen Zhen, Guangdong, China.
Medicine (Baltimore). 2024 Dec 13;103(50):e40841. doi: 10.1097/MD.0000000000040841.
This case report aims to enhance understanding of pancreatobiliary maljunction (PBM) and promote more proactive treatment.
The patient, a 24-year-old Chinese female, was admitted to the hospital on April 7, 2020, due to "recurrent abdominal pain for over 2 years, with a recent episode accompanied by nausea and vomiting for 1 day." She had a previous history of gallstones.
The initial diagnosis upon admission was biliary acute pancreatitis. During the emergency endoscopic retrograde cholangiopancreatography (ERCP) procedure, anatomical abnormalities were discovered. Intraoperative endoscopic ultrasonography led to a diagnosis of complex PBM (JSPBM, type D) + choledochal cyst (Todani, Ic) + incomplete pancreatic divisum + early chronic pancreatitis. These diagnoses were confirmed by postoperative magnetic resonance cholangiopancreatography.
After multiple conservative treatments such as ERCP with accessory pancreatic duct stent placement, the patient underwent surgical treatment in April 2021, which included "laparoscopic left hemihepatectomy + choledochal cyst excision + cholecystectomy + hepatic portal cholangioplasty."
The patient has not experienced any abdominal pain since the surgery and is currently under regular follow-up.
Endoscopic ultrasound is effective for the diagnoses of complex PBM and incomplete pancreatic divisum. ERCP with pancreatic duct stent placement and surgical procedure is reliable for relieving the patient's symptoms.
本病例报告旨在加深对胰胆管合流异常(PBM)的理解,并促进更积极的治疗。
该患者为一名24岁的中国女性,于2020年4月7日因“反复腹痛2年余,近期发作伴恶心、呕吐1天”入院。她既往有胆结石病史。
入院时初步诊断为胆源性急性胰腺炎。在急诊内镜逆行胰胆管造影(ERCP)过程中,发现了解剖异常。术中内镜超声检查诊断为复杂型PBM(JSPBM,D型)+胆总管囊肿(Todani,Ic型)+胰腺分裂不全+早期慢性胰腺炎。术后磁共振胰胆管造影证实了这些诊断。
在进行了如ERCP并放置副胰管支架等多种保守治疗后,患者于2021年4月接受了手术治疗,包括“腹腔镜左半肝切除术+胆总管囊肿切除术+胆囊切除术+肝门胆管成形术”。
患者术后未再出现腹痛,目前正在定期随访中。
内镜超声对复杂型PBM和胰腺分裂不全的诊断有效。ERCP放置胰管支架及手术操作对缓解患者症状可靠。