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EClinicalMedicine. 2022 Jul 1;50:101505. doi: 10.1016/j.eclinm.2022.101505. eCollection 2022 Aug.
2
Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial.稳定型心绞痛患者的经皮冠状动脉介入治疗（ORBITA）：一项双盲、随机对照试验。
Lancet. 2018 Jan 6;391(10115):31-40. doi: 10.1016/S0140-6736(17)32714-9. Epub 2017 Nov 2.
3
Blinding measured: a systematic review of randomized controlled trials of acupuncture.盲法测量：针灸随机对照试验的系统评价。
Evid Based Complement Alternat Med. 2013;2013:708251. doi: 10.1155/2013/708251. Epub 2013 Mar 3.
4
Comparison of biomechanical properties between acupuncture and non-penetrating sham needle.针刺与非穿透假针刺的生物力学特性比较。
Complement Ther Med. 2011 Jan;19 Suppl 1:S8-S12. doi: 10.1016/j.ctim.2010.09.002. Epub 2010 Oct 14.
5
Acupuncture for treating dry eye: a randomized placebo-controlled trial.针刺治疗干眼症：一项随机安慰剂对照试验。
Acta Ophthalmol. 2010 Dec;88(8):e328-33. doi: 10.1111/j.1755-3768.2010.02027.x. Epub 2010 Nov 10.
6
Fifteen-day acupuncture treatment relieves diabetic peripheral neuropathy.为期15天的针灸治疗可缓解糖尿病周围神经病变。
J Acupunct Meridian Stud. 2010 Jun;3(2):95-103. doi: 10.1016/S2005-2901(10)60018-0.
7
Towards a proposal for assessment of blinding success in clinical trials: up-to-date review.评估临床试验中盲法成功的建议：最新综述。
Community Dent Oral Epidemiol. 2009 Dec;37(6):477-84. doi: 10.1111/j.1600-0528.2009.00494.x. Epub 2009 Sep 15.
8
Acupuncture versus sham acupuncture for chronic prostatitis/chronic pelvic pain.针刺疗法与假针刺疗法治疗慢性前列腺炎/慢性盆腔疼痛的比较
Am J Med. 2008 Jan;121(1):79.e1-7. doi: 10.1016/j.amjmed.2007.07.033.
9
A double-blind placebo needle for acupuncture research.用于针灸研究的双盲安慰剂针。
BMC Complement Altern Med. 2007 Oct 10;7:31. doi: 10.1186/1472-6882-7-31.
10
Assessment of blinding may be inappropriate after the trial.试验结束后进行盲法评估可能并不合适。
Contemp Clin Trials. 2005 Aug;26(4):512-4; author reply 514-5. doi: 10.1016/j.cct.2005.04.002.

一种用于随机对照试验的简易盲法指标。

A simple blinding index for randomized controlled trials.

作者信息

Petroff David, Bacak Miroslav, Dagres Nikolaos, Dilk Patrick, Wachter Rolf

机构信息

Clinical Trial Centre, Faculty of Medicine, Leipzig University, Germany.

Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany.

出版信息

Contemp Clin Trials Commun. 2024 Nov 26;42:101393. doi: 10.1016/j.conctc.2024.101393. eCollection 2024 Dec.

DOI:10.1016/j.conctc.2024.101393
PMID:39686958
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11647154/
Abstract

Blinding is an essential part of many randomized controlled trials. However, its quality is usually not checked, and when it is, common measures are the James index and/or the Bang index. In the present paper we discuss these two indices, providing examples demonstrating their considerable weaknesses and limitations, and propose an alternative method for measuring blinding. We argue that this new approach has a number of advantages. We also provide an R-package for computing our blinding index.

摘要

盲法是许多随机对照试验的重要组成部分。然而，其质量通常未经检查，即便进行检查，常用的指标是詹姆斯指数和/或邦指数。在本文中，我们讨论这两个指数，给出示例说明它们存在的显著弱点和局限性，并提出一种测量盲法的替代方法。我们认为这种新方法有诸多优点。我们还提供了一个用于计算我们的盲法指数的R包。