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Treatment of recalcitrant discoid lupus erythematosus with roflumilast 0.3% cream following suboptimal response to anifrolumab and improvement of hypopigmentation.

作者信息

Garg Kareena S, Tjahjono Leonardo A

机构信息

Georgetown University School of Medicine, Washington, District of Columbia.

Department of Dermatology, School of Medicine and Health Sciences, The George Washington University, Washington, District of Columbia.

出版信息

JAAD Case Rep. 2024 Oct 9;54:50-52. doi: 10.1016/j.jdcr.2024.09.016. eCollection 2024 Dec.

DOI:10.1016/j.jdcr.2024.09.016
PMID:39687066
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11647105/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a52/11647105/24c2f05de918/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a52/11647105/24c2f05de918/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a52/11647105/24c2f05de918/gr1.jpg

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本文引用的文献

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BMJ Case Rep. 2024 Jun 18;17(6):e258487. doi: 10.1136/bcr-2023-258487.
2
The role of cAMP dependent gene transcription in lupus pathophysiology.
Clin Immunol. 2024 May;262:110179. doi: 10.1016/j.clim.2024.110179. Epub 2024 Mar 8.
3
Case series of anifrolumab for treatment of cutaneous lupus erythematosus and lupus-related mucocutaneous manifestations in patients with SLE.系统性红斑狼疮患者用阿尼鲁单抗治疗红斑狼疮皮疹和狼疮相关黏膜表现的病例系列
Lupus Sci Med. 2023 Dec 19;10(2):e001007. doi: 10.1136/lupus-2023-001007.
4
Successful treatment of severe chronic cutaneous lupus with anifrolumab: A series of 6 cases.用阿尼氟单抗成功治疗重度慢性皮肤型狼疮：6例病例系列
JAAD Case Rep. 2023 May 4;37:21-29. doi: 10.1016/j.jdcr.2023.04.024. eCollection 2023 Jul.
5
Roflumilast enhances the melanogenesis and attenuates oxidative stress-triggered damage in melanocytes.罗氟司特可增强黑素细胞的黑色素生成，并减轻氧化应激引发的损伤。
J Dermatol Sci. 2023 May;110(2):44-52. doi: 10.1016/j.jdermsci.2023.04.001. Epub 2023 Apr 3.
6
Rapid efficacy of anifrolumab across multiple subtypes of recalcitrant cutaneous lupus erythematosus parallels changes in discrete subsets of blood transcriptomic and cellular biomarkers.阿尼鲁单抗在多种难治性皮肤红斑狼疮亚型中的快速疗效与血液转录组和细胞生物标志物离散亚群的变化平行。
Br J Dermatol. 2023 Jul 17;189(2):210-218. doi: 10.1093/bjd/ljad089.
7
Treatment With Anifrolumab for Discoid Lupus Erythematosus.阿尼鲁单抗治疗盘状红斑狼疮
JAMA Dermatol. 2023 Feb 1;159(2):224-226. doi: 10.1001/jamadermatol.2022.5242.
8
Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases.用于治疗炎症性疾病的磷酸二酯酶-4抑制剂
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