Nielsen J B, Taagehøj-Jensen F, Andresen J H, Jørgensen T M, Djurhuus J C, Sørensen S S, Charles P
J Urol. 1985 Feb;133(2):179-82. doi: 10.1016/s0022-5347(17)48871-9.
In 61 patients with vesicoureteral reflux renal scar formation was diagnosed by excretory urography and 123iodine-hippurate scintigrams. Scar formation on the nephrograms was detected in the upper, middle and lower zones of the kidneys on tomography exposures. Scintigraphic detection of scars was performed on the computerized uptake of the parenchymal phase. Maximal time elapse between the 2 investigations was 1 year. Excretory urography revealed 37 kidneys with a total of 74 regional scars. On scintigraphy 57 kidneys were judged to have 102 scars. There were 281 regions judged to be identical on the scintigram and the nephrogram. A true positive ratio (sensitivity) of 0.46 and a true negative ratio (specificity) of 0.90 were noted for the excretory urogram, compared to a sensitivity of 0.64 and a specificity of 0.81 for renography. The study confirms an over-representation of scars judged from scintigrams, which calls for further investigation of scar formation detection.
在61例膀胱输尿管反流患者中，通过排泄性尿路造影和123碘马尿酸盐闪烁扫描诊断出肾瘢痕形成。在断层摄影曝光时，在肾脏的上、中、下区域检测到肾图上的瘢痕形成。在实质期的计算机摄取上进行瘢痕的闪烁扫描检测。两次检查之间的最大时间间隔为1年。排泄性尿路造影显示37个肾脏共有74个区域瘢痕。闪烁扫描显示57个肾脏有102个瘢痕。在闪烁扫描图和肾图上有281个区域被判定为相同。排泄性尿路造影的真阳性率（敏感性）为0.46，真阴性率（特异性）为0.90，而肾造影的敏感性为0.64，特异性为0.81。该研究证实，从闪烁扫描图判断的瘢痕过多，这需要对瘢痕形成检测进行进一步研究。
