嗜铬细胞瘤伴高钙血症：病例报告及文献复习

Pheochromocytoma with hypercalcemia: case report and review of literature.

作者信息

Shanberg A M, Baghdassarian R, Tansey L A, Bacon D, Greenberg P, Perley M

出版信息

J Urol. 1985 Feb;133(2):258-9. doi: 10.1016/s0022-5347(17)48909-9.

Abstract

We report a case of severe hypercalcemia and a pheochromocytoma of the right adrenal gland. The patient underwent adrenalectomy, following which the hypercalcemia disappeared. Parathormone assay of the adrenal tumor revealed high levels of activity despite normal serum parathormone activity. This suggests that the etiology of hypercalcemia in patients with pheochromocytoma is related to ectopic secretion of a parathormone ectopic peptide-like substance.

摘要

我们报告一例严重高钙血症合并右肾上腺嗜铬细胞瘤的病例。患者接受了肾上腺切除术，术后高钙血症消失。对肾上腺肿瘤进行甲状旁腺素检测发现，尽管血清甲状旁腺素活性正常，但肿瘤中的甲状旁腺素活性水平很高。这表明嗜铬细胞瘤患者高钙血症的病因与一种甲状旁腺素异位肽样物质的异位分泌有关。