Kobayashi Yuta, Enta Yusuke, Nakashima Masaki, Tada Norio
Department of Cardiology, Sendai Kousei Hospital, 1-20, Tsutsumidori Amamiya-cho, Aoba-ku, Sendai, Miyagi 981-0914, Japan.
Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan.
Eur Heart J Case Rep. 2024 Dec 6;8(12):ytae643. doi: 10.1093/ehjcr/ytae643. eCollection 2024 Dec.
Balloon-assisted bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary artery obstruction (BA-BASILICA) enables valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) in patients at risk of coronary artery obstruction. However, its efficacy in patients with severely calcified leaflets remains unclear.
We report a 78-year-old woman with a deteriorated 21 mm Carpentier-Edwards PERIMOUNT Magna valve. Computed tomography showed severe calcification in the left coronary leaflet, extending above the left coronary artery (LCA) ostium, with a virtual transcatheter heart valve to coronary ostium distance of 3.7 mm, indicating a high risk of coronary obstruction after ViV-TAVI. We performed ViV-TAVI using the BA-BASILICA because of the patient's high surgical risks. Traversal of the calcified leaflet was successfully achieved using both en face and side views to visualize the traversal system's position in an area without calcification and in front of the LCA. After traversal, the leaflet was dilated with a balloon and accidentally split into two. A 20 mm SAPIEN 3 Ultra RESILIA valve was deployed. Despite initial procedural success, severe LCA stenosis developed due to leaflet compression. This was resolved by orthotopic stenting using an en face view to identify cells not covered by the bioprosthetic leaflet generated by BA-BASILICA.
To our knowledge, this is the first report of ViV-TAVI using the BA-BASILICA with an en face view of severely calcified leaflets. This case suggests that BA-BASILICA with an en face view could be effective for patients at high risk of coronary obstruction with severely calcified leaflets.
球囊辅助生物瓣或自体主动脉瓣叶有意撕裂以预防医源性冠状动脉阻塞(BA - BASILICA)技术可使有冠状动脉阻塞风险的患者接受经导管主动脉瓣置换术(ViV - TAVI)。然而,其在严重钙化瓣叶患者中的疗效尚不清楚。
我们报告一名78岁女性,其21毫米Carpentier - Edwards PERIMOUNT Magna瓣膜功能恶化。计算机断层扫描显示左冠状动脉瓣叶严重钙化,延伸至左冠状动脉(LCA)开口上方,虚拟经导管心脏瓣膜至冠状动脉开口距离为3.7毫米,提示ViV - TAVI术后冠状动脉阻塞风险高。由于患者手术风险高,我们采用BA - BASILICA技术进行ViV - TAVI。通过正面和侧面视图成功穿过钙化瓣叶,以可视化穿过系统在无钙化区域且位于LCA前方的位置。穿过之后,用球囊扩张瓣叶,瓣叶意外裂为两半。植入一枚20毫米SAPIEN 3 Ultra RESILIA瓣膜。尽管手术初期成功,但因瓣叶受压导致严重的LCA狭窄。通过使用正面视图进行原位支架置入解决了这一问题,以识别未被BA - BASILICA产生的生物瓣叶覆盖的细胞。
据我们所知,这是首例使用BA - BASILICA技术并对严重钙化瓣叶采用正面视图进行ViV - TAVI的报告。该病例表明,对于有严重钙化瓣叶且冠状动脉阻塞风险高的患者,采用正面视图的BA - BASILICA技术可能有效。