Mason R A, Arbeit L A, Giron F
JAMA. 1985 Feb 15;253(7):1001-4.
Acute renal failure has been observed in patients undergoing angiography in which a hypertonic triiodinated contrast medium is used. To ascertain the incidence of renal dysfunction and the clinical risk factors, we did a prospective study in which creatinine clearance was measured before and immediately after 120 arteriographic procedures. Thirty-seven patients (31%) sustained a significant reduction in creatine clearance after arteriography. No specific risk factor could be determined. Our findings, however, indicate that patients with preexisting renal insufficiency or diabetes mellitus are not at a higher risk for sustaining a fall in creatinine clearance after angiography.
在接受血管造影术且使用高渗性三碘造影剂的患者中，已观察到急性肾衰竭。为确定肾功能不全的发生率及临床风险因素，我们进行了一项前瞻性研究，在120例血管造影术前及术后即刻测量肌酐清除率。37例患者（31%）在血管造影术后肌酐清除率显著降低。无法确定具体的风险因素。然而，我们的研究结果表明，已有肾功能不全或糖尿病的患者在血管造影术后肌酐清除率下降的风险并不更高。
