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First-in-human SPECT/CT imaging of [At]PSMA-5: targeted alpha therapy in a patient with refractory prostate cancer.

作者信息

Watabe Tadashi, Hatano Koji, Naka Sadahiro, Sasaki Hidetaka, Kamiya Takashi, Shirakami Yoshifumi, Toyoshima Atsushi, Cardinale Jens, Giesel Frederik L, Isohashi Kayako, Nonomura Norio, Tomiyama Noriyuki

机构信息

Department of Radiology, Graduate School of Medicine, Osaka University, Suita, Japan.

Institute for Radiation Sciences, Osaka University, Suita, Japan.

出版信息

Eur J Nucl Med Mol Imaging. 2025 Jun;52(7):2253-2255. doi: 10.1007/s00259-024-07017-w. Epub 2024 Dec 17.

DOI:10.1007/s00259-024-07017-w
PMID:39688698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12119378/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/12119378/371bdd39f51b/259_2024_7017_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/12119378/371bdd39f51b/259_2024_7017_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/12119378/371bdd39f51b/259_2024_7017_Figa_HTML.jpg

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本文引用的文献

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Targeted α-therapy using astatine (At)-labeled PSMA1, 5, and 6: a preclinical evaluation as a novel compound.使用放射性碘[^125^I]标记的 PSMA1、5 和 6 的靶向 α 疗法:作为一种新型化合物的临床前评估。
Eur J Nucl Med Mol Imaging. 2023 Feb;50(3):849-858. doi: 10.1007/s00259-022-06016-z. Epub 2022 Nov 8.