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成年脊柱畸形男性患者:人口统计学、影像学及并发症方面的性别差异。

Male patients with adult spinal deformity: sex differences in demographics, radiography, and complications.

作者信息

Wei Xuepeng, Yoshida Go, Hasegawa Tomohiko, Yamato Yu, Banno Tomohiro, Arima Hideyuki, Oe Shin, Ide Koichiro, Yamada Tomohiro, Kurosu Kenta, Matsuyama Yukihiro

机构信息

Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-Ku, Hamamatsu City, Shizuoka, 431-3192, Japan.

Division of Geriatric Musculoskeletal Health, Hamamatsu University School of Medicine, Hamamatsu City, Shizuoka, Japan.

出版信息

Spine Deform. 2025 May;13(3):903-910. doi: 10.1007/s43390-024-01023-6. Epub 2024 Dec 17.

Abstract

PURPOSE

This study aimed to investigate sex-related differences in demographics, radiography, and perioperative complications in adult spinal deformity (ASD) surgeries.

METHODS

This retrospective cohort, single-center study enrolled patients who underwent long-instrumented fusion from the thoracic spine to the ilium for ASD, with a minimum follow-up of 2 years. The incidence of preoperative comorbidities, perioperative complications, and postoperative mechanical complications was analyzed.

RESULTS

Of the 323 patients, ASD was more common in females (85.8%). The T-score in female patients was lower than that in male patients (-1.6 ± 1.1 vs.- 0.8 ± 1.0, p = 0.02). Male patients demonstrated lower rates of degenerative kyphoscoliosis (83.4% vs. 65.2%, p = 0.004) but higher rates of neuromuscular disease (7.6% vs. 21.7%, p = 0.003) than female patients. Male patients exhibited higher prevalence of cardiovascular disease (4.0% vs. 13.5%, p = 0.034) and hemodialysis (2.5% vs. 10.8%, p = 0.035). Additionally, male patients had a higher Charlson Comorbidity Index than female patients (0.8 ± 1.1 vs. 1.4 ± 1.1, p = 0.001). Moreover, male patients showed higher perioperative complications in surgical site infection (5.1% vs. 15.2%, p = 0.018). However, the incidence of proximal junctional failure (43.3% vs. 39.1%, p = 0.595) and rod fracture (27.8% vs. 26.1%, p = 0.81) was not different.

CONCLUSIONS

Male patients with ASD demonstrated frequent pathology of neuromuscular disease, preoperative comorbidities, and surgical site infection, necessitating careful preoperative checkups and intraoperative care.

摘要

目的

本研究旨在调查成人脊柱畸形(ASD)手术中人口统计学、影像学及围手术期并发症方面的性别差异。

方法

本回顾性队列单中心研究纳入了接受从胸椎至髂骨长节段器械融合术治疗ASD且随访至少2年的患者。分析术前合并症、围手术期并发症及术后机械性并发症的发生率。

结果

在323例患者中,ASD在女性中更为常见(85.8%)。女性患者的T值低于男性患者(-1.6±1.1 vs. -0.8±1.0,p = 0.02)。男性患者退行性脊柱侧后凸发生率较低(83.4%对65.2%,p = 0.004),但神经肌肉疾病发生率高于女性患者(7.6%对21.7%,p = 0.003)。男性患者心血管疾病(4.0%对13.5%,p = 0.034)和血液透析(2.5%对10.8%,p = 0.035)的患病率更高。此外,男性患者的Charlson合并症指数高于女性患者(0.8±1.1对1.4±1.1,p = 0.001)。而且,男性患者手术部位感染的围手术期并发症更高(5.1%对15.2%,p = 0.018)。然而,近端交界性失败(43.3%对39.1%,p = 0.595)和棒材骨折(27.8%对26.1%,p = 0.81)的发生率无差异。

结论

患有ASD的男性患者神经肌肉疾病、术前合并症及手术部位感染的情况较为常见,因此术前需仔细检查并给予术中精心护理。

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