Takagi H, Morimoto T, Yasue M, Kato K, Yamada E, Suzuki R
J Surg Oncol. 1985 Jan;28(1):59-62. doi: 10.1002/jso.2930280114.
Thirteen patients with advanced carcinoma of the lower colon and no evidence of extrapelvic metastasis were submitted to total pelvic exenteration. Nine of the 13 patients had ureteral urinary diversion by the ileal segment conduit. Three had colonic conduit bladder using the terminal portion of the descending colon. One patient had bilateral uretero colonic anastomosis. The operative mortality rate was 7.7%. Determinate 5-year survival rate of 38.5% was achieved. Histological examinations of the surgical specimen revealed associated abscesses adjacent to the tumor in six cases, although the cancer extended to the bowel wall and adhered to the surrounding structures in all specimens. Total pelvic exenteration assures a better quality of life, lessening of symptoms, disease control and, in selected patients, a cure.
13例低位结肠癌患者，无盆腔外转移证据，接受了全盆腔脏器切除术。13例患者中有9例采用回肠段导管进行输尿管尿路改道。3例采用降结肠末端构建结肠导管膀胱。1例患者进行了双侧输尿管结肠吻合术。手术死亡率为7.7%。5年确定生存率达到38.5%。手术标本的组织学检查显示，6例患者的肿瘤旁伴有脓肿，尽管所有标本中的癌症均已侵犯肠壁并与周围结构粘连。全盆腔脏器切除术可确保更好的生活质量、减轻症状、控制疾病，在部分患者中可实现治愈。
