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内质网锚定蛋白对生长素反应因子凝聚的调控

Endoplasmic reticulum-anchored proteins in control of AUXIN RESPONSE FACTOR condensation.

作者信息

Schindfessel Cédric, Vanneste Steffen

机构信息

Department of Plant and Crops, Fac Bioscience Engineering, Ghent University, Ghent, Belgium.

Department of Plant and Crops, Fac Bioscience Engineering, Ghent University, Ghent, Belgium.

出版信息

Dev Cell. 2024 Dec 16;59(24):3192-3194. doi: 10.1016/j.devcel.2024.11.004.

Abstract

Sequestration of AUXIN RESPONSE FACTOR (ARF) transcription factors in cytoplasmic condensates represents a specialized mechanism for modulating cellular auxin responsiveness. In this issue of Developmental Cell, Xuan et al. show that MULTIPLE C2-DOMAIN AND TRANSMEMBRANE REGION PROTEIN (MCTP) proteins stimulate lateral root development by antagonizing ARF7 and ARF19 condensation.

摘要

生长素响应因子(ARF)转录因子在细胞质凝聚物中的隔离是调节细胞生长素反应性的一种特殊机制。在本期《发育细胞》中,Xuan等人表明,多C2结构域和跨膜区域蛋白(MCTP)通过拮抗ARF7和ARF19凝聚来刺激侧根发育。

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