Pereira-Bazurdo A N, Cadavid-Restrepo G E, Arango-Isaza R E, Moreno-Herrera C X
Microbiodiversity and bioprospection research group, Laboratorio de Biología Celular 19A-310, Molecular, Facultad de Ciencias, Universidad Nacional de Colombia Sede Medellín, 050034, Colombia.
Plant Biotechnology UNALMED-CIB group, Laboratorio de Ecología y Evolución de Insectos 16-223, Facultad de Ciencias, Universidad Nacional de Colombia, Sede Medellín, 050034, Colombia.
Biotechnol Rep (Amst). 2024 Nov 29;45:e00866. doi: 10.1016/j.btre.2024.e00866. eCollection 2025 Mar.
The control of avocado pests and diseases heavily relies on the use of several types of pesticides, some of which are strictly monitored or not internationally accepted. New sources of bioactive molecules produced by phytopathogen-inhibiting microorganisms offer an excellent alternative for the control of pests and diseases. This study explores the potential antagonistic action against phytopathogenic microorganisms, using bacterial strains obtained from avocado thrips. In addition, we detected and identified quorum sensing (QS) signaling molecules that are related to virulence factors and antibiotic production. The results showed that , and strains exhibited antagonism against five fungal phytopathogens. Additionally, some bacteria also produce specific signaling molecules like N-3-(oxododecanoyl)-l-homoserine lactone (OdDHL), N-(3-oxo)-hexanoyl l-HL (OHHL), 4‑hydroxy-2-heptylquinoline (HHQ) or 2-heptyl-3,4-dihydroxyquinoline (PQS, Pseudomonas quinolone signal), cyclo(L-Phe-l-Pro), and cyclo(L-Pro-l-Tyr, which might give them antimicrobial properties. This research explores the biotechnological potential of these bacteria in fighting the diseases affecting avocados in Colombia.
鳄梨病虫害的防治严重依赖于多种类型农药的使用，其中一些受到严格监管或未被国际认可。由抑制植物病原体的微生物产生的生物活性分子新来源为病虫害防治提供了极佳的替代方案。本研究利用从鳄梨蓟马中获得的细菌菌株，探索其对植物致病微生物的潜在拮抗作用。此外，我们检测并鉴定了与毒力因子和抗生素产生相关的群体感应（QS）信号分子。结果表明， 菌株对五种真菌植物病原体表现出拮抗作用。此外，一些细菌还产生特定的信号分子，如N-3-（氧代十二烷酰基）-L-高丝氨酸内酯（OdDHL）、N-（3-氧代）-己酰基-L-高丝氨酸内酯（OHHL）、4-羟基-2-庚基喹啉（HHQ）或2-庚基-3,4-二羟基喹啉（PQS，铜绿假单胞菌喹诺酮信号）、环（L-苯丙氨酸-L-脯氨酸）和环（L-脯氨酸-L-酪氨酸），这些可能赋予它们抗菌特性。本研究探索了这些细菌在对抗哥伦比亚鳄梨病害方面的生物技术潜力。
