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走出诊断迷宫:一例新冠后腱鞘炎病例

Navigating the Diagnostic Maze: A Case of Post-COVID-19 Tenosynovitis.

作者信息

Puspalingam Kasture, Suppamutharwyam Malarkodi

机构信息

Medical, Selayang General Hospital, Kuala Lumpur, MYS.

Geriatrics, Selayang General Hospital, Kuala Lumpur, MYS.

出版信息

Cureus. 2024 Nov 17;16(11):e73849. doi: 10.7759/cureus.73849. eCollection 2024 Nov.

DOI:10.7759/cureus.73849
PMID:39691137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11651336/
Abstract

Post-COVID-19 sequelae can include various complications, including musculoskeletal manifestations. Unvaccinated against COVID-19, a 21-year-old woman initially experienced severe COVID-19 and subsequently recovered. She later developed mild COVID-19, which was followed by severe myalgia and joint pain in her upper extremities. After a third COVID-19 infection, she experienced intense pain in multiple hand joints and lethargy. The blood tests were normal, and the ultrasound report revealed tenosynovitis of the wrist joint. Her pain improved with combined treatment approaches.  To our knowledge, this is the first case report of post-COVID-19 tenosynovitis. We have also highlighted the predisposing factors for the development of tenosynovitis, which may include being unvaccinated and lifestyle changes, such as a sedentary routine. This case also emphasizes the need for further research into the long-term effects of the condition on mobility and quality of life.

摘要

新冠后遗症可能包括各种并发症,包括肌肉骨骼表现。一名21岁未接种新冠疫苗的女性最初感染了重症新冠,随后康复。她后来又感染了轻症新冠,之后出现了上肢严重肌痛和关节疼痛。在第三次感染新冠后,她多个手部关节剧痛并伴有乏力。血液检查正常,超声报告显示腕关节腱鞘炎。综合治疗方法使她的疼痛有所改善。据我们所知,这是首例新冠后腱鞘炎病例报告。我们还强调了腱鞘炎发生的易感因素,可能包括未接种疫苗以及生活方式改变,如久坐不动。该病例还强调了有必要进一步研究此病状对活动能力和生活质量的长期影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e3a/11651336/e6b9ac6e4b02/cureus-0016-00000073849-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e3a/11651336/e6b9ac6e4b02/cureus-0016-00000073849-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e3a/11651336/e6b9ac6e4b02/cureus-0016-00000073849-i01.jpg

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本文引用的文献

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Post-Acute COVID-19 Joint Pain and New Onset of Rheumatic Musculoskeletal Diseases: A Systematic Review.新冠后关节疼痛与风湿性肌肉骨骼疾病的新发:一项系统综述
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Musculoskeletal Consequences of COVID-19.肌肉骨骼系统 COVID-19 的后果。
J Bone Joint Surg Am. 2020 Jul 15;102(14):1197-1204. doi: 10.2106/JBJS.20.00847.
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Organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19.血管紧张素转换酶 2 的器官保护作用及其对 COVID-19 预后的影响。
J Med Virol. 2020 Jul;92(7):726-730. doi: 10.1002/jmv.25785. Epub 2020 Apr 5.
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)进入细胞依赖于 ACE2 和 TMPRSS2,可被一种临床验证的蛋白酶抑制剂所阻断。
Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052. Epub 2020 Mar 5.