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磁共振引导的立体定向体部放射治疗用于肾细胞癌胰腺寡转移灶

Magnetic resonance-guided stereotactic body radiation therapy for pancreatic oligometastases from renal cell carcinoma.

作者信息

van Vulpen Jonna K, Eijkelenkamp Hidde, Grimbergen Guus, Wessels Frank J, Mulder Sasja F, Meijer Gert J, Intven Martijn P W

机构信息

Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.

Department of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.

出版信息

Phys Imaging Radiat Oncol. 2024 Nov 28;32:100683. doi: 10.1016/j.phro.2024.100683. eCollection 2024 Oct.

DOI:10.1016/j.phro.2024.100683
PMID:39691188
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11650256/
Abstract

Stereotactic body radiation therapy (SBRT) may be a non-invasive strategy to treat patients with pancreatic oligometastases from renal cell carcinoma (RCC). We analyzed 11 patients treated with MR-guided SBRT to 31 pancreatic oligometastases. At a median follow-up of 31.6 months, 1-year and 2-year freedom from local progression was 100 % and 95 % (95 % CI 86-100 %), respectively. Moreover, 1-year and 2-year freedom from systemic therapy was 91 % (95 %CI 75-100 %) and 82 % (95 % CI 62-100 %), respectively. MR-guided SBRT may be a safe and effective treatment option for pancreatic oligometastases from RCC.

摘要

立体定向体部放射治疗(SBRT)可能是一种治疗肾细胞癌(RCC)胰腺寡转移患者的非侵入性策略。我们分析了11例接受磁共振引导下SBRT治疗31个胰腺寡转移灶的患者。中位随访31.6个月时,1年和2年局部无进展率分别为100%和95%(95%CI 86-100%)。此外,1年和2年无需全身治疗率分别为91%(95%CI 75-100%)和82%(95%CI 62-100%)。磁共振引导下SBRT可能是RCC胰腺寡转移的一种安全有效的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/f922944caa37/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/f82f9bf1099d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/c5ff8fb950a2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/7c20e82876d8/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/f922944caa37/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/f82f9bf1099d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/c5ff8fb950a2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/7c20e82876d8/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc02/11650256/f922944caa37/fx2.jpg

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Front Oncol. 2023 Oct 3;13:1040673. doi: 10.3389/fonc.2023.1040673. eCollection 2023.
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