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美国急诊科收治的急性胃肠炎伴血性腹泻儿童的病因

Etiologies of Bloody Diarrhea in Children Presenting With Acute Gastroenteritis to US Emergency Departments.

作者信息

Fonseca-Romero Paola, Brintz Ben J, Vierkant D Matthew, Dien Bard Jennifer, Cohen Daniel M, Festekjian Ara, Leber Amy L, Jackson Jami T, Kanwar Neena, Larsen Chari, Selvarangan Rangaraj, Chapin Kimberle C, Pavia Andrew T, Ahmed Sharia M, Leung Daniel T

机构信息

Department of Pathology, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.

Department of Internal Medicine, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.

出版信息

Open Forum Infect Dis. 2024 Nov 27;11(12):ofae692. doi: 10.1093/ofid/ofae692. eCollection 2024 Dec.

DOI:10.1093/ofid/ofae692
PMID:39691289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11651156/
Abstract

We used molecular testing to examine the causes of bloody diarrhea in a multicenter study of pediatric gastroenteritis. Pathogens typically associated with bloody diarrhea were detected in less than half of cases, and inappropriate antibiotic use was common, supporting the use of stool testing in patients with bloody diarrhea.

摘要

在一项关于小儿肠胃炎的多中心研究中，我们采用分子检测来探究血性腹泻的病因。在不到半数的病例中检测到了通常与血性腹泻相关的病原体，且抗生素使用不当的情况很常见，这支持了对血性腹泻患者进行粪便检测。

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Etiologies of Bloody Diarrhea in Children Presenting With Acute Gastroenteritis to US Emergency Departments.美国急诊科收治的急性胃肠炎伴血性腹泻儿童的病因
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本文引用的文献

1
Clinical Impact of Multiplex Molecular Diagnostic Testing in Children With Acute Gastroenteritis Presenting to an Emergency Department: A Multicenter Prospective Study.多联分子诊断检测在儿科急诊急性胃肠炎患儿中的临床影响：一项多中心前瞻性研究。
Clin Infect Dis. 2024 Mar 20;78(3):573-581. doi: 10.1093/cid/ciad710.
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Etiology, Presentation, and Risk Factors for Diarrheal Syndromes in 3 Sub-Saharan African Countries After the Introduction of Rotavirus Vaccines From the Vaccine Impact on Diarrhea in Africa (VIDA) Study.腹泻综合征的病因、表现及危险因素：3 个撒哈拉以南非洲国家在引入轮状病毒疫苗后的情况，来自非洲疫苗对腹泻影响（VIDA）研究。
Clin Infect Dis. 2023 Apr 19;76(76 Suppl 1):S12-S22. doi: 10.1093/cid/ciad022.
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Comparison of a Rapid Multiplex Gastrointestinal Panel with Standard Laboratory Testing in the Management of Children with Hematochezia in a Pediatric Emergency Department: Randomized Controlled Trial.儿科急诊中便血患儿采用快速多重胃肠道panel 与标准实验室检测对比的管理：随机对照试验。
Microbiol Spectr. 2023 Jun 15;11(3):e0026823. doi: 10.1128/spectrum.00268-23. Epub 2023 Apr 11.
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Antibiotic prescribing for acute gastroenteritis during ambulatory care visits-United States, 2006-2015.在门诊就诊期间治疗急性肠胃炎的抗生素处方-美国，2006-2015 年。
Infect Control Hosp Epidemiol. 2022 Dec;43(12):1880-1889. doi: 10.1017/ice.2021.522. Epub 2022 Aug 26.
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Hematochezia in children with acute diarrhea seeking emergency department care - a prospective cohort study.因急性腹泻前往急诊科就诊的儿童便血——一项前瞻性队列研究。
Acad Emerg Med. 2022 Apr;29(4):429-441. doi: 10.1111/acem.14434. Epub 2022 Feb 8.
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Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016.估计 195 个国家的全球、区域和国家腹泻发病率、死亡率和病因：2016 年全球疾病负担研究的系统分析。
Lancet Infect Dis. 2018 Nov;18(11):1211-1228. doi: 10.1016/S1473-3099(18)30362-1. Epub 2018 Sep 19.
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2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea.2017 年美国传染病学会临床实践指南：感染性腹泻的诊断与管理。
Clin Infect Dis. 2017 Nov 29;65(12):e45-e80. doi: 10.1093/cid/cix669.
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J Pediatric Infect Dis Soc. 2017 Sep 1;6(3):231-238. doi: 10.1093/jpids/piw020.
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Shiga Toxin-Producing Escherichia coli Infection, Antibiotics, and Risk of Developing Hemolytic Uremic Syndrome: A Meta-analysis.产志贺毒素大肠杆菌感染、抗生素与溶血尿毒综合征发生风险：一项荟萃分析
Clin Infect Dis. 2016 May 15;62(10):1251-1258. doi: 10.1093/cid/ciw099. Epub 2016 Feb 24.
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J Clin Microbiol. 2015 Mar;53(3):915-25. doi: 10.1128/JCM.02674-14. Epub 2015 Jan 14.