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选择合适的路径:剑突下与肋间外侧入路在前纵隔肿物切除术中的结果

Choosing the proper path: outcomes of subxiphoid vs. lateral intercostal approaches in the resection of anterior mediastinal masses.

作者信息

Leng Xuechun, Chen Mengzou, Zhang Yang, Gao Jian, You Zhenbing, Hu Zhongwu

机构信息

Department of Thoracic Surgery, The Affiliated Huaian No.1 People's Hospital, Nanjing Medical University, Huai'an, Jiangsu, China.

Department of Anesthesiology, The Affiliated Huaian No.1 People's Hospital, Nanjing Medical University, Huai'an, Jiangsu, China.

出版信息

Front Surg. 2024 Dec 3;11:1463881. doi: 10.3389/fsurg.2024.1463881. eCollection 2024.

DOI:10.3389/fsurg.2024.1463881
PMID:39691683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11649629/
Abstract

BACKGROUND

While the subxiphoid approach (SA) in thoracoscopic thymectomy offers benefits in terms of fat removal and pain reduction, it remains unclear which patients with anterior mediastinal masses benefit most from the subxiphoid vs. the lateral intercostal approach (LA).

METHODS

This retrospective study analyzed patients treated for anterior mediastinal masses at our center from January 2019 to December 2023. Patients were categorized into two groups based on the surgical approach: SA (35 cases) and LA (56 cases). Demographic data, clinical characteristics, perioperative metrics, and short-term outcomes were compared.

RESULTS

Ninety-one patients were included, with diagnoses including thymic cysts (43), thymomas types A, AB, and B1 (24), B2 thymomas (18), thymic carcinoma (6).No significant differences were found between the groups in terms of gender, age, tumor size, body mass index, conversion to sternotomy, or blood loss. The LA group, however, experienced shorter surgical durations ( < 0.001), less drainage ( = 0.021), shorter hospital stays ( < 0.001), and lower hospitalization costs ( = 0.024). Pain scores on the visual analogue scale were similar between groups on the day of surgery and the first postoperative day.

CONCLUSION

The findings suggest that the lateral intercostal approach is preferable for patients with thymic cysts and Masaoka stage I-II thymomas without myasthenia gravis due to its efficiency and cost-effectiveness.

摘要

背景

虽然胸腔镜胸腺切除术的剑突下入路(SA)在脂肪清除和疼痛减轻方面具有优势,但对于前纵隔肿块患者,剑突下入路与外侧肋间入路(LA)相比,哪类患者获益最大仍不明确。

方法

这项回顾性研究分析了2019年1月至2023年12月在本中心接受前纵隔肿块治疗的患者。根据手术入路将患者分为两组:剑突下入路(35例)和外侧肋间入路(56例)。比较了人口统计学数据、临床特征、围手术期指标和短期结局。

结果

纳入91例患者,诊断包括胸腺囊肿(43例)、A、AB和B1型胸腺瘤(24例)、B2型胸腺瘤(18例)、胸腺癌(6例)。两组在性别、年龄、肿瘤大小、体重指数、转为胸骨切开术或失血量方面无显著差异。然而,外侧肋间入路组手术时间较短(<0.001)、引流量较少(=0.021)、住院时间较短(<0.001)、住院费用较低(=0.024)。手术当天和术后第一天,两组视觉模拟量表疼痛评分相似。

结论

研究结果表明,对于胸腺囊肿和无重症肌无力的Masaoka I-II期胸腺瘤患者,外侧肋间入路因其效率和成本效益而更可取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb56/11649629/898f4cbc4904/fsurg-11-1463881-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb56/11649629/898f4cbc4904/fsurg-11-1463881-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb56/11649629/898f4cbc4904/fsurg-11-1463881-g001.jpg

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本文引用的文献

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Subxiphoid versus lateral intercostal thoracoscopic thymectomy for suspected thymoma: Results of a randomized controlled trial.剑突下入路与侧胸壁入路电视胸腔镜胸腺切除术治疗疑似胸腺瘤:一项随机对照试验的结果。
J Thorac Cardiovasc Surg. 2024 Jul;168(1):290-298. doi: 10.1016/j.jtcvs.2023.10.040. Epub 2023 Oct 27.
2
Combining the best of both worlds: sternal elevation for resection of anterior mediastinal tumors through the subxiphoidal uniportal video-assisted thoracoscopic surgery approach.融合两全其美之法:经剑突下单孔电视辅助胸腔镜手术入路行胸骨抬高术以切除前纵隔肿瘤
J Thorac Dis. 2023 Sep 28;15(9):4573-4576. doi: 10.21037/jtd-23-1167. Epub 2023 Aug 25.
3
A uniport subxiphoid approach with a modified sternum retractor is safe and feasible for anterior mediastinal tumors.
采用改良胸骨牵开器的剑突下单切口入路对于前纵隔肿瘤是安全可行的。
J Thorac Dis. 2023 Mar 31;15(3):1364-1372. doi: 10.21037/jtd-23-244.
4
Subxiphoid-subcostal versus transthoracic thoracoscopic thymectomy: A safe and feasible approach.剑突下-肋下与经胸电视胸腔镜胸腺切除术:一种安全可行的方法。
JTCVS Tech. 2022 Sep 13;16:172-181. doi: 10.1016/j.xjtc.2022.08.017. eCollection 2022 Dec.
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Efficiency of ectopic thymectomy by three surgical approaches in non-thymomatous myasthenia gravis.三种手术入路行胸腺切除术治疗非胸腺瘤性重症肌无力的疗效。
Updates Surg. 2022 Aug;74(4):1435-1443. doi: 10.1007/s13304-022-01295-5. Epub 2022 Jun 23.
6
Thymomectomy versus complete thymectomy in early-stage non-myasthenic thymomas: a multicentric propensity score-matched study.胸腺切除术与早期非重症肌无力胸腺瘤的全胸腺切除术:一项多中心倾向评分匹配研究。
Interact Cardiovasc Thorac Surg. 2022 Jun 15;35(1). doi: 10.1093/icvts/ivac167.
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Management of incidentally detected small anterior mediastinal nodules: Which way to go?偶然发现的小型前纵隔结节的处理:该如何选择?
Lung Cancer. 2022 Jun;168:30-35. doi: 10.1016/j.lungcan.2022.04.007. Epub 2022 Apr 18.
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Short-term analysis of uniport video-assisted thoracoscopic surgery via the subxiphoid approach without chest tube drainage for anterior mediastinal tumors: a comparative retrospective study.剑突下入路单孔电视胸腔镜手术治疗前纵隔肿瘤不放置胸腔闭式引流的短期分析:一项比较性回顾性研究
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J Chest Surg. 2021 Apr 5;54(2):127-136. doi: 10.5090/jcs.20.140.