Dajani Jana, Shakhshir Ali, Sawalmeh Ayham, Awashra Ameer, Dweekat Mo'tasem, Al-Ali Khaled, Adnan Fatayer Ahmad Mohammad
Department of Medicine, An-Najah National University, Nablus, Palestine.
Ministry of Health, Preventive Medicine Department, Nablus, Palestine.
Radiol Case Rep. 2024 Nov 30;20(2):1135-1140. doi: 10.1016/j.radcr.2024.10.151. eCollection 2025 Feb.
Nontuberculous mycobacteria (NTM) are a diverse group of environmental mycobacteria found ubiquitously in soil and water, causing infections that typically arise from environmental exposure rather than person-to-person transmission. This case report documents the first known detection of in our region, emphasizing the clinical challenges and diagnostic complexities associated with NTM infections. The case involves a 37-year-old male with a significant smoking history who presented with progressively worsening cough, significant weight loss, and bilateral cavitary lung lesions. Initial diagnostic efforts, including tests for tuberculosis and malignancy, were inconclusive. However, subsequent bronchoalveolar lavage confirmed the presence of , leading to a year-long treatment regimen. This report signifies a critical step in recognizing the burden of NTM infections in region, a region where comprehensive epidemiological data are lacking. The rising global incidence of NTM lung disease and its association with underlying lung conditions and immunocompromised states further underscore the importance of this case, particularly given the diagnostic overlap with more common conditions like tuberculosis. This case calls attention to the need for optimized local diagnostic criteria and the potential for NTM to be a causative agent of community-acquired pneumonia.
非结核分枝杆菌(NTM)是一类多样的环境分枝杆菌,广泛存在于土壤和水中,其引起的感染通常源于环境暴露而非人际传播。本病例报告记录了在我们地区首次发现的已知病例,强调了与NTM感染相关的临床挑战和诊断复杂性。该病例涉及一名有大量吸烟史的37岁男性,他出现了逐渐加重的咳嗽、显著体重减轻和双侧肺空洞病变。最初的诊断努力,包括结核病和恶性肿瘤检测,均无定论。然而,随后的支气管肺泡灌洗证实了 的存在,从而导致了为期一年的治疗方案。本报告标志着在认识该地区NTM感染负担方面迈出了关键一步,该地区缺乏全面的流行病学数据。NTM肺病全球发病率的上升及其与潜在肺部疾病和免疫功能低下状态的关联进一步凸显了该病例的重要性,特别是考虑到与结核病等更常见疾病的诊断重叠。该病例提醒人们需要优化当地的诊断标准,以及NTM作为社区获得性肺炎病原体的可能性。