Tucker Jacqueline, Ruszkay Nicole, Sandifer Sara, King Tonya S, Goyal Neerav, Goldenberg David, Gniady John P
College of Medicine Pennsylvania State University Hershey Pennsylvania USA.
Department of Otolaryngology-Head and Neck Surgery Penn State Hershey Medical Center Hershey Pennsylvania USA.
Laryngoscope Investig Otolaryngol. 2024 Dec 17;9(6):e70038. doi: 10.1002/lio2.70038. eCollection 2024 Dec.
To compare patient outcomes across body mass index (BMI) subgroups in the setting of recent tracheotomy.
This retrospective chart review included patients over 18 years old who underwent tracheotomy placement between February 2017 and March 2020. Patients were divided into five groups based on BMI: underweight, normal weight, overweight, obese, and morbidly obese. Data were collected from the electronic medical record (EMR). Statistical analyses were completed via Kruskal-Wallis, Chi-square, log-rank tests, and Cox proportional hazards regression. If significant differences were found between groups, then subsequent pairwise comparisons of BMI were completed.
There were 391 patients included in the study. There were significant differences in length of stay ( = .015) and duration of mechanical ventilation ( < .001) among the groups. This was mainly driven by comparisons between the normal weight and obese groups, with patients of normal weight having shorter hospital stays and shorter ventilation durations. With each increasing BMI category from normal weight, a greater proportion of patients were ventilator-dependent at the time of discharge ( < .001). Interestingly, after adjustment for comorbidities, the rate of tracheotomy change was 0.86 times lower for every increase in BMI category (95% CI 0.77-0.96). There was a significant difference among the BMI groups with respect to time to tracheotomy collar placement according to both the log-rank test ( < .001) and the Cox model with adjustment for the presence of heart failure ( = .011).
Among patients undergoing tracheotomy, obese and morbidly obese patients have increased lengths of hospital stays. Additionally, they are dependent on ventilators for longer and are more likely to be ventilator-dependent at the time of discharge. It is important to understand how BMI impacts the hospital course for patients undergoing tracheotomy so that patients and their families can be better informed.
Level 3.
比较近期行气管切开术患者不同体重指数(BMI)亚组的患者预后。
这项回顾性病历审查纳入了2017年2月至2020年3月期间接受气管切开术的18岁以上患者。根据BMI将患者分为五组:体重过轻、正常体重、超重、肥胖和病态肥胖。数据从电子病历(EMR)中收集。通过Kruskal-Wallis检验、卡方检验、对数秩检验和Cox比例风险回归进行统计分析。如果组间发现显著差异,则随后完成BMI的两两比较。
本研究共纳入391例患者。各组之间的住院时间(P = 0.015)和机械通气时间(P < 0.001)存在显著差异。这主要是由正常体重组和肥胖组之间的比较驱动的,正常体重患者的住院时间和通气时间较短。随着BMI类别从正常体重开始每增加一级,出院时依赖呼吸机的患者比例更高(P < 0.001)。有趣的是,在调整合并症后,BMI类别每增加一级,气管切开术更换率降低0.86倍(95%可信区间0.77 - 0.96)。根据对数秩检验(P < 0.001)和调整心力衰竭存在情况的Cox模型(P = 0.011),BMI组在气管切开套管放置时间方面存在显著差异。
在接受气管切开术的患者中,肥胖和病态肥胖患者的住院时间延长。此外,他们依赖呼吸机的时间更长,出院时更有可能依赖呼吸机。了解BMI如何影响气管切开术患者的住院过程很重要,以便患者及其家属能够得到更好的信息。
3级。