体外膜肺氧合支持期间的抗凝监测：监测还是抛硬币决定？
Anticoagulation Monitoring During ECMO Support: Monitor or Flip a Coin?
作者信息
Rajsic Sasa, Treml Benedikt
机构信息
Department of Anaesthesiology and Intensive Care Medicine, Medical University Innsbruck, Innsbruck, Austria.
出版信息
Clin Cardiol. 2024 Dec;47(12):e70061. doi: 10.1002/clc.70061.
Abstract
Should we rely on anticoagulation monitoring in ECMO patients or simply flip a coin? The increasing use of anti-factor Xa activity to monitor the effect of UFH appears appropriate, given its moderate correlation with the UFH infusion rates, and it may play a role in preventing thromboembolic events. However, to avoid bleeding complications, more sophisticated tools, and careful clinical decision-making remain essential.
摘要
我们应该依靠对体外膜肺氧合（ECMO）患者进行抗凝监测，还是干脆抛硬币决定？鉴于抗Xa因子活性与普通肝素（UFH）输注速率具有中等相关性，越来越多地使用抗Xa因子活性来监测UFH的效果似乎是合适的，并且它可能在预防血栓栓塞事件中发挥作用。然而，为避免出血并发症，更精密的工具以及谨慎的临床决策仍然至关重要。
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