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子宫体癌的腹主动脉旁淋巴结放疗

Paraaortic lymph node radiotherapy in cancer of the uterine corpus.

作者信息

Potish R A, Twiggs L B, Adcock L L, Savage J E, Levitt S H, Prem K A

出版信息

Obstet Gynecol. 1985 Feb;65(2):251-6.

PMID:3969238
Abstract

From 1973 through 1982, 48 women received 4500 to 5075 rads to the paraaortic lymph nodes as part of their primary management for cancer of the uterine corpus. One patient developed severe enteric morbidity. Five-year survival rates were 52% in the total group, 57% in clinically staged patients, and 47% in surgically staged patients. Patients with surgically confirmed pelvic lymphatic spread had a five-year survival rate of 67%. Patients with surgically confirmed paraaortic spread alone or pelvic and paraaortic spread had five-year survival rates of 47 and 43%, respectively. Eighty-eight percent of recurrences were outside of the radiation portals. In contradistinction to much of the last decade's literature, radiation therapy has salvaged a substantial fraction of patients with nodal metastases, and morbidity rates have been acceptable.

摘要

从1973年到1982年,48名女性接受了4500至5075拉德的腹主动脉旁淋巴结放疗,作为其子宫体癌初始治疗的一部分。1例患者出现严重的肠道并发症。全组5年生存率为52%,临床分期患者为57%,手术分期患者为47%。手术证实有盆腔淋巴转移的患者5年生存率为67%。手术证实仅有腹主动脉旁转移或盆腔及腹主动脉旁转移的患者5年生存率分别为47%和43%。88%的复发发生在放疗野之外。与过去十年的许多文献不同,放射治疗挽救了相当一部分有淋巴结转移的患者,且发病率是可接受的。

相似文献

1
Paraaortic lymph node radiotherapy in cancer of the uterine corpus.子宫体癌的腹主动脉旁淋巴结放疗
Obstet Gynecol. 1985 Feb;65(2):251-6.
2
FIGO stage IIIC endometrial carcinoma with metastases confined to pelvic lymph nodes: analysis of treatment outcomes, prognostic variables, and failure patterns following adjuvant radiation therapy.国际妇产科联盟(FIGO)IIIC期子宫内膜癌,转移局限于盆腔淋巴结:辅助放疗后的治疗结果、预后变量及失败模式分析
Gynecol Oncol. 1999 Nov;75(2):211-4. doi: 10.1006/gyno.1999.5569.
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Extent of disease as an indication for pelvic radiation following radical hysterectomy and bilateral pelvic lymph node dissection in the treatment of stage IB and IIA cervical carcinoma.在治疗IB期和IIA期宫颈癌时,根治性子宫切除术后盆腔放疗的指征——疾病范围及双侧盆腔淋巴结清扫情况
Gynecol Oncol. 1994 Jul;54(1):4-9. doi: 10.1006/gyno.1994.1157.
4
[Surgical and radiologic treatment of cancer of the uterine body. Results of 12 years].[子宫体癌的手术及放射治疗。12年的结果]
Minerva Med. 1993 Nov;84(11):603-14.
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The incidence of isolated paraaortic nodal metastasis in surgically staged endometrial cancer patients with negative pelvic lymph nodes.盆腔淋巴结阴性的手术分期子宫内膜癌患者中孤立性腹主动脉旁淋巴结转移的发生率。
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Cervical cancer with paraaortic metastases: significance of residual paraaortic disease after surgical staging.伴有腹主动脉旁转移的宫颈癌:手术分期后腹主动脉旁残留病灶的意义
Gynecol Oncol. 1998 Jun;69(3):243-7. doi: 10.1006/gyno.1998.5012.
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Radical cystectomy and extended pelvic lymphadenectomy: survival of patients with lymph node metastasis above the bifurcation of the common iliac vessels treated with surgery only.根治性膀胱切除术和扩大盆腔淋巴结清扫术:仅接受手术治疗的髂总血管分叉以上淋巴结转移患者的生存率。
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[Prognostic factors in uterine cervical and corpus cancer].[子宫颈癌和子宫体癌的预后因素]
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Long-term results of maximally aggressive trimodality therapy in a high-risk subset of early-stage cervical cancer patients.早期宫颈癌高危亚组患者接受最大程度积极三联疗法的长期结果。
J Reprod Med. 2006 May;51(5):383-8.

引用本文的文献

1
Treatment for advanced and recurrent endometrial carcinoma: combined modalities.治疗晚期和复发性子宫内膜癌:联合治疗模式。
Oncologist. 2010;15(8):852-61. doi: 10.1634/theoncologist.2010-0091. Epub 2010 Jul 21.
2
The impact of the absolute number and ratio of positive lymph nodes on survival of endometrioid uterine cancer patients.阳性淋巴结的绝对数量和比例对子宫内膜样子宫癌患者生存的影响。
Br J Cancer. 2007 Sep 3;97(5):605-11. doi: 10.1038/sj.bjc.6603898. Epub 2007 Jul 31.
3
Lymphadenectomy and adjuvant therapy in endometrial carcinoma: role of adjuvant chemotherapy.
子宫内膜癌的淋巴结切除术及辅助治疗:辅助化疗的作用
Br J Cancer. 2002 Aug 12;87(4):377-80. doi: 10.1038/sj.bjc.6600468.
4
Treatment of node-positive endometrial cancer with complete node dissection, chemotherapy and radiation therapy.采用完全淋巴结清扫术、化疗和放射治疗对淋巴结阳性子宫内膜癌进行治疗。
Br J Cancer. 1997;75(12):1836-41. doi: 10.1038/bjc.1997.313.
5
Pathophysiology and management of endometrial hyperplasia and carcinoma.子宫内膜增生和癌的病理生理学与管理
West J Med. 1990 Jul;153(1):50-61.