Potish R A, Twiggs L B, Adcock L L, Savage J E, Levitt S H, Prem K A
Obstet Gynecol. 1985 Feb;65(2):251-6.
From 1973 through 1982, 48 women received 4500 to 5075 rads to the paraaortic lymph nodes as part of their primary management for cancer of the uterine corpus. One patient developed severe enteric morbidity. Five-year survival rates were 52% in the total group, 57% in clinically staged patients, and 47% in surgically staged patients. Patients with surgically confirmed pelvic lymphatic spread had a five-year survival rate of 67%. Patients with surgically confirmed paraaortic spread alone or pelvic and paraaortic spread had five-year survival rates of 47 and 43%, respectively. Eighty-eight percent of recurrences were outside of the radiation portals. In contradistinction to much of the last decade's literature, radiation therapy has salvaged a substantial fraction of patients with nodal metastases, and morbidity rates have been acceptable.
从1973年到1982年,48名女性接受了4500至5075拉德的腹主动脉旁淋巴结放疗,作为其子宫体癌初始治疗的一部分。1例患者出现严重的肠道并发症。全组5年生存率为52%,临床分期患者为57%,手术分期患者为47%。手术证实有盆腔淋巴转移的患者5年生存率为67%。手术证实仅有腹主动脉旁转移或盆腔及腹主动脉旁转移的患者5年生存率分别为47%和43%。88%的复发发生在放疗野之外。与过去十年的许多文献不同,放射治疗挽救了相当一部分有淋巴结转移的患者,且发病率是可接受的。