Shi Qiuyin, Wang Xuefei, Zhao Dongxia, Tang Weihong, Mo Yongzhen
Department of Cardiology, Zhongda Hospital Affiliated to Southeast University.
Nursing Teaching and Research Department, Jiangsu Province Official Hospital, Nanjing, Jiangsu, China.
Coron Artery Dis. 2025 Jun 1;36(4):303-311. doi: 10.1097/MCA.0000000000001478. Epub 2024 Dec 18.
To assess the impact of perceived stress levels in patients undergoing percutaneous coronary intervention (PCI) on the occurrence of major adverse cardiovascular events (MACEs) within a 6-month follow-up period postprocedure.
A cohort of 339 hospitalized patients with coronary heart disease undergoing initial PCI was prospectively enrolled in the Department of Cardiology at two branches of Zhongda Hospital Affiliated to Southeast University between January 2022 and July 2022. Baseline data including demographic and clinical characteristics, along with the Chinese Perceived Stress Scale (CPSS), were collected. The occurrence of MACE was evaluated at 3 and 6 months post-PCI. Kaplan-Meier survival analysis and Cox regression models were engaged to analyze the relationship between perceived stress and MACE within 6 months after PCI.
MACE occurred in 16.22% (55/339) of patients during the 6 following months. High CPSS at baseline was significantly associated with an increasing risk of short-term MACE occurrence (HR: 6.48, 95% confidence interval: 2.98-14.11, P < 0.05).
High perceived stress during the baseline period after PCI was significantly correlated with increased incidence of MACE within 6 months postprocedure. The perceived stress level could help to identify patients undergoing PCI at heightened risk of short-term MACE.
评估接受经皮冠状动脉介入治疗（PCI）的患者感知压力水平对术后6个月随访期内主要不良心血管事件（MACE）发生情况的影响。
2022年1月至2022年7月期间，在东南大学附属中大医院两个院区的心内科前瞻性纳入了339例首次接受PCI的住院冠心病患者。收集包括人口统计学和临床特征在内的基线数据，以及中国感知压力量表（CPSS）。在PCI术后3个月和6个月评估MACE的发生情况。采用Kaplan-Meier生存分析和Cox回归模型分析PCI术后6个月内感知压力与MACE之间的关系。
在随后的6个月内，16.22%（55/339）的患者发生了MACE。基线时CPSS较高与短期MACE发生风险增加显著相关（HR：6.48，95%置信区间：2.98-14.11，P<0.05）。
PCI术后基线期的高感知压力与术后6个月内MACE发生率增加显著相关。感知压力水平有助于识别接受PCI的短期MACE风险较高的患者。
