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闭角型青光眼的微创青光眼手术

Minimally invasive glaucoma surgery in angle closure.

作者信息

Chan Nicole Shu-Wen, Sng Chelvin C A

机构信息

Department of Ophthalmology, National University Hospital.

Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore.

出版信息

Curr Opin Ophthalmol. 2025 Mar 1;36(2):152-158. doi: 10.1097/ICU.0000000000001117. Epub 2024 Dec 18.

Abstract

PURPOSE OF REVIEW

This review discusses the evidence on the efficacy, safety and role of minimally invasive glaucoma surgery (MIGS) in eyes with angle closure glaucoma. While cataract surgery remains the most established surgical treatment for primary angle closure glaucoma (PACG), the intraocular pressure (IOP) may remain elevated after cataract surgery despite open angles due to trabecular meshwork damage from chronic iridotrabecular contact.

RECENT FINDINGS

There is emerging evidence that combining cataract surgery with MIGS in eyes with PACG, though an off-label indication for some MIGS devices, can achieve greater IOP and glaucoma medication reduction than cataract surgery alone.

SUMMARY

Trabecular bypass MIGS procedures and less destructive forms of ciliary body treatment have been shown to be effective in PACG and are safer alternatives to traditional incisional surgeries. Evidence for the use of subconjunctival MIGS and suprachoroidal MIGS in angle closure eyes is lacking at present, and further investigation is indicated.

摘要

综述目的

本综述探讨了微创青光眼手术(MIGS)在闭角型青光眼患者中的疗效、安全性及作用的相关证据。尽管白内障手术仍是原发性闭角型青光眼(PACG)最成熟的手术治疗方法,但由于慢性虹膜小梁接触导致小梁网受损,白内障手术后即使房角开放,眼压仍可能升高。

最新发现

有新证据表明,在PACG患者眼中,将白内障手术与MIGS联合进行,虽然对一些MIGS设备来说属于超适应证使用,但与单纯白内障手术相比,能更大程度地降低眼压并减少青光眼药物使用。

总结

小梁旁路MIGS手术及对睫状体破坏性较小的治疗方式已被证明在PACG中有效,并且是传统切开手术更安全的替代方法。目前缺乏在闭角型眼中使用结膜下MIGS和脉络膜上腔MIGS的证据,需要进一步研究。

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