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Beyond traditional hypoxemia metrics: hypoxic burden as a predictor of cognitive dysfunction in sleep apnea.

作者信息

Leonhard Aristotle G, Kapur Vishesh K

机构信息

The Division of Pulmonary, Critical Care, and Sleep Medicine, The University of Washington, Seattle, WA, USA.

出版信息

Sleep. 2025 Mar 11;48(3). doi: 10.1093/sleep/zsae292.

DOI:10.1093/sleep/zsae292
PMID:39693413
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11893529/
Abstract
摘要

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2
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J Clin Sleep Med. 2025 Mar 1;21(3):457-466. doi: 10.5664/jcsm.11422.
3
Hypoxemia during rapid eye movement sleep mediates memory impairment in older adults at risk for dementia via CA1 hippocampal volume loss.快速眼动睡眠期间的低氧血症通过 CA1 海马体积损失介导痴呆风险老年人的记忆障碍。
Eur J Neurol. 2024 Dec;31(12):e16491. doi: 10.1111/ene.16491. Epub 2024 Sep 20.
4
Older adults at greater risk for Alzheimer's disease show stronger associations between sleep apnea severity in REM sleep and verbal memory.老年人群患阿尔茨海默病的风险较高，其 REM 睡眠中睡眠呼吸暂停严重程度与言语记忆之间的相关性更强。
Alzheimers Res Ther. 2024 May 9;16(1):102. doi: 10.1186/s13195-024-01446-3.
5
Obstructive sleep apnoea and 5-year cognitive decline in the elderly.阻塞性睡眠呼吸暂停与老年人 5 年认知能力下降。
Eur Respir J. 2023 Apr 27;61(4). doi: 10.1183/13993003.01621-2022. Print 2023 Apr.
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Thromb Haemost. 2023 Apr;123(4):393-401. doi: 10.1055/a-2000-8288. Epub 2022 Dec 19.
7
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