Liu Kai, Chen Caizhong, Shen Tingting, Wen Xixi, Zeng Mengsu, Xu Pengju
Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, China.
Shanghai United Imaging Healthcare Co., Ltd., Shanghai, China.
Magn Reson Imaging. 2025 Apr;117:110312. doi: 10.1016/j.mri.2024.110312. Epub 2024 Dec 16.
The aim of this study was to evaluate a novel respiratory frequency-modulated continuous-wave radar-trigger (FT) technique for multiple -b-value diffusion-weighted imaging (DWI) of liver and compare it with conventional free breathing (FB) DWI technique.
39 patients with focal liver lesions underwent both frequency-modulated continuous-wave radar-trigger (FT) and conventional free-breathing (FB) multi-b-value diffusion-weighted imaging (DWI,b = 0,50,400,800 s/mm. Two abdominal radiologists independently assessed the quality of liver DWI images obtained using both techniques, measured and compared liver signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) at different b-values, as well as apparent diffusion coefficient (ADC) values calculated from all b-values.
In terms of image quality, the FT technique is superior to the conventional FB technique, with overall image quality scores (Reader 1, 3.56 ± 0.50 and Reader 2, 3.59 ± 0.55)vs (Reader 1, 2.90 ± 0.75 and Reader 2, 2.97 ± 0.71), respectively. The liver SNR (at b-values of 50,400,and 800 s/mm) obtained by FT was (138.5 ± 43.48, 96.67 ± 31.95, 71.54 ± 22.03), respectively, which was significantly higher than that obtained by conventional FB (110.90 ± 39.28, 80.86 ± 29.13, 60.43 ± 18.61, P < 0.05). The lesion CNR with FT was significantly higher than that with conventional FB (258.99 ± 151.38 vs 174.60 ± 99.90; 164.56 ± 87.25 vs 111.12 ± 42.43; 118.83 ± 68.76 vs 76.01 ± 35.48, P < 0.001). There was no significant difference in ADC values of liver and lesions between the two techniques: ADCliver-L and ADCliver-R: (FT 1479.3 ± 270.0 vs FB 1529.3 ± 275.5 and FT 1219.6 ± 127.4 vs FB 1248.7 ± 168.2, P > 0.05); ADC lesion:FT(969.0 ± 261.3) vs FB (1017.5 ± 240.4, P > 0.05).
For multi-b-value liver diffusion-weighted imaging, FT technique has higher image quality and better lesion visibility than conventional FB technique and there is no significant difference in ADC values of liver and lesions between the two techniques.
本研究旨在评估一种新型呼吸频率调制连续波雷达触发（FT）技术用于肝脏多b值扩散加权成像（DWI），并将其与传统自由呼吸（FB）DWI技术进行比较。
39例肝脏局灶性病变患者接受了频率调制连续波雷达触发（FT）和传统自由呼吸（FB）多b值扩散加权成像（DWI，b = 0、50、400、800 s/mm²）。两位腹部放射科医生独立评估两种技术获得的肝脏DWI图像质量，测量并比较不同b值下肝脏的信噪比（SNR）和对比噪声比（CNR），以及根据所有b值计算的表观扩散系数（ADC）值。
在图像质量方面，FT技术优于传统FB技术，总体图像质量评分（读者1，3.56±0.50；读者2，3.59±0.55）对比（读者1，2.90±0.75；读者2，2.97±0.71）。FT获得的肝脏SNR（b值为50、400和800 s/mm²时）分别为（138.5±43.48、96.67±31.95、71.54±22.03），显著高于传统FB获得的（110.90±39.28、80.86±29.13、60.43±18.61，P<0.05）。FT的病变CNR显著高于传统FB（258.99±151.38对比174.60±99.90；164.56±87.25对比111.12±42.43；118.83±68.76对比76.01±35.48，P<0.001）。两种技术之间肝脏和病变的ADC值无显著差异：肝左叶和肝右叶的ADC值（FT 1479.3±270.0对比FB 1529.3±275.5；FT 1219.6±127.4对比FB 1248.7±168.2，P>0.05）；病变ADC值：FT（969.0±261.3）对比FB（1017.5±240.4，P>0.05）。
对于多b值肝脏扩散加权成像，FT技术比传统FB技术具有更高的图像质量和更好的病变可视性，且两种技术之间肝脏和病变的ADC值无显著差异。
