Raatz Sarah, Freese Rebecca L, Jang Subin, Kunin-Batson Alicia, Gross Amy C, Bensignor Megan O
Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, Minnesota, USA.
Center for Pediatric Obesity Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Child Obes. 2025 Jun;21(4):365-371. doi: 10.1089/chi.2024.0351. Epub 2024 Dec 18.
There are now four FDA-approved anti-obesity medications (AOMs) for youth ≥12 years, which can be effective therapies to treat obesity and obesity-related comorbidities. This study describes parent/guardian (caregiver) openness to using AOMs for adolescents with obesity and evaluates factors that may contribute to openness. Caregivers of adolescents aged 12-17 years were surveyed. Self-reported height, weight, demographic information, family, and personal history of obesity or obesity-related comorbidities were collected. Participants rated their openness to starting an AOM for their child for obesity alone or obesity-related comorbidities on a 7-point Likert scale. A Likert rating of less than 4 was considered "less open" versus 4-7 was considered "more open." A total of 344 participants completed the survey. Average openness toward AOM use for obesity as the only indication (as opposed to comorbid conditions) was 3.2 ± 1.74. Caregivers who were knowledgeable that the FDA-approved AOM use in adolescents had greater odds of being open to using these medications compared with caregivers who were not knowledgeable (odds ratio: 2.18; 95% confidence interval: 1.25-2.86). Caregivers reported openness to starting an AOM if they had prior knowledge of these medications, highlighting the need for family education on AOM use and indications.
目前有四种已获美国食品药品监督管理局(FDA)批准的用于12岁及以上青少年的抗肥胖药物(AOMs),它们可以有效治疗肥胖症及与肥胖相关的合并症。本研究描述了父母/监护人(照料者)对肥胖青少年使用AOMs的接受程度,并评估了可能影响接受程度的因素。对12至17岁青少年的照料者进行了调查。收集了自我报告的身高、体重、人口统计学信息、家庭情况以及肥胖或与肥胖相关合并症的个人病史。参与者在7分李克特量表上对为孩子开始使用AOMs治疗单纯肥胖或与肥胖相关合并症的接受程度进行评分。李克特评分低于4分被认为“接受程度较低”,而4至7分被认为“接受程度较高”。共有344名参与者完成了调查。仅将AOMs用于治疗肥胖(而非合并症)时,平均接受程度为3.2±1.74。了解FDA已批准在青少年中使用AOMs的照料者比不了解的照料者更有可能接受使用这些药物(优势比:2.18;95%置信区间:1.25 - 2.86)。照料者表示,如果他们事先了解这些药物,就会接受为孩子开始使用AOMs,这突出了对家庭进行AOMs使用和适应症方面健康教育的必要性。