• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

源于恶性结肠穿孔的下肢坏死性筋膜炎:一种罕见模式。

Lower limb necrotising fasciitis descending from malignant colonic perforation: a rare pattern.

作者信息

Robbie Elliot, Desai Seema, Ramavath Ashok

机构信息

Obstetrics and Gynaecology, Lewisham and Greenwich NHS Trust, London, UK

Trauma and Orthopaedics, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK.

出版信息

BMJ Case Rep. 2024 Dec 18;17(12):e262470. doi: 10.1136/bcr-2024-262470.

DOI:10.1136/bcr-2024-262470
PMID:39694653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11667148/
Abstract

Necrotising fasciitis (NF) is a rare surgical emergency characterised by soft tissue necrosis and systemic compromise. Typically it originates following adjacent skin and soft tissue insult; however, our unusual case required a high index of clinical suspicion to avert potential mortality. A man in his 60s with diabetes mellitus presented with 2 weeks of knee pain, swelling and necrotic skin on the posterior calf. X-ray demonstrated subcutaneous emphysema. Initial debridement confirmed extensive necrotising fasciitis of the whole lower limb with tracking through femoral canal into the abdomen. CT confirmed sigmoid colon perforation. Both life-saving Hartmann's and hip disarticulation procedures were performed with good outcomes. Histology confirmed locally invasive sigmoid colon adenocarcinoma. Our case highlights lower limb necrotising fasciitis as a rare complication secondary to sigmoid perforation associated with malignancy. In cases where the infection nidus cannot be identified, an abdominal source should be considered.

摘要

坏死性筋膜炎(NF)是一种罕见的外科急症,其特征为软组织坏死和全身功能障碍。通常它继发于邻近的皮肤和软组织损伤;然而,我们这个不寻常的病例需要高度的临床怀疑才能避免潜在的死亡。一名60多岁的糖尿病男性患者,出现膝关节疼痛、肿胀以及小腿后侧皮肤坏死2周。X线显示皮下气肿。初步清创证实整个下肢广泛坏死性筋膜炎,并经股管蔓延至腹部。CT证实乙状结肠穿孔。同时进行了挽救生命的哈特曼手术和髋关节离断术,效果良好。组织学证实为局部浸润性乙状结肠腺癌。我们的病例强调了下肢坏死性筋膜炎是与恶性肿瘤相关的乙状结肠穿孔继发的罕见并发症。在无法确定感染灶的情况下,应考虑腹部来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/36b5cefdf7d2/bcr-17-12-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/ce1bd83f1fd6/bcr-17-12-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/060512a734ba/bcr-17-12-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/08c2332a36ad/bcr-17-12-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/a4892e8eafc6/bcr-17-12-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/fd0767b0bae4/bcr-17-12-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/8f715bd48274/bcr-17-12-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/2693e7c37df7/bcr-17-12-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/222c98581bf7/bcr-17-12-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/0b078e271a47/bcr-17-12-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/36b5cefdf7d2/bcr-17-12-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/ce1bd83f1fd6/bcr-17-12-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/060512a734ba/bcr-17-12-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/08c2332a36ad/bcr-17-12-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/a4892e8eafc6/bcr-17-12-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/fd0767b0bae4/bcr-17-12-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/8f715bd48274/bcr-17-12-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/2693e7c37df7/bcr-17-12-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/222c98581bf7/bcr-17-12-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/0b078e271a47/bcr-17-12-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac8/11667148/36b5cefdf7d2/bcr-17-12-g010.jpg

相似文献

1
Lower limb necrotising fasciitis descending from malignant colonic perforation: a rare pattern.源于恶性结肠穿孔的下肢坏死性筋膜炎:一种罕见模式。
BMJ Case Rep. 2024 Dec 18;17(12):e262470. doi: 10.1136/bcr-2024-262470.
2
Necrotising fasciitis of the thigh secondary to colonic perforation: the femoral canal as a route for infective spread.大腿坏疽性筋膜炎继发于结肠穿孔:股管作为感染传播途径。
J Plast Reconstr Aesthet Surg. 2012 Dec;65(12):1731-3. doi: 10.1016/j.bjps.2012.04.006. Epub 2012 Apr 25.
3
Not your usual hip pain: necrotising fasciitis secondary to sigmoid perforation.不寻常的髋部疼痛:乙状结肠穿孔继发坏死性筋膜炎。
BMJ Case Rep. 2019 Mar 14;12(3):e228985. doi: 10.1136/bcr-2018-228985.
4
Necrotizing fasciitis of the lower extremity secondary to a perforated rectosigmoid tumor.下肢坏死性筋膜炎继发于穿孔的直肠乙状结肠肿瘤。
Indian J Cancer. 2021 Oct-Dec;58(4):603-607. doi: 10.4103/ijc.IJC_670_20.
5
[Complicated diverticular disease debuting as necrotising fasciitis of pelvic limb. A case report].[以盆腔肢体坏死性筋膜炎为首发表现的复杂性憩室病。病例报告]
Cir Cir. 2017 May-Jun;85(3):240-244. doi: 10.1016/j.circir.2016.01.003. Epub 2016 Mar 31.
6
[Necrotising inflammations of the lower extremities due to gastrointestinal perforations].
Zentralbl Chir. 2011 Feb;136(1):82-3. doi: 10.1055/s-0030-1262685. Epub 2011 Jan 24.
7
Necrotising fasciitis of the thigh secondary to a perforated rectal cancer.继发于穿孔性直肠癌的大腿坏死性筋膜炎。
J Plast Reconstr Aesthet Surg. 2009 Feb;62(2):e17-9. doi: 10.1016/j.bjps.2007.08.031. Epub 2008 Mar 3.
8
Emergency hip disarticulations for severe necrotising fasciitis of the lower limb: a series of rare cases from a rural district general hospital.下肢严重坏死性筋膜炎的急诊髋关节离断术:来自一家农村地区综合医院的一系列罕见病例
Ann R Coll Surg Engl. 2021 Jul;103(7):e223-e226. doi: 10.1308/rcsann.2021.0079.
9
Sigmoid colon perforation from an impacted toothpick and an occult colonic malignancy.牙签嵌顿导致乙状结肠穿孔并隐匿性结肠恶性肿瘤。
Am Surg. 2013 Aug;79(8):E273-4.
10
Necrotising fasciitis of the left leg caused by perforated caecal adenocarcinoma.由盲肠腺癌穿孔引起的左腿坏死性筋膜炎。
Ann R Coll Surg Engl. 2017 Nov;99(8):e223-e224. doi: 10.1308/rcsann.2017.0138. Epub 2017 Sep 15.

本文引用的文献

1
Presentation and management of a case of rectal cancer complicated by perforation and necrotizing soft tissue infection.一例直肠癌合并穿孔及坏死性软组织感染的病例介绍与处理
J Surg Case Rep. 2022 Jul 30;2022(7):rjac318. doi: 10.1093/jscr/rjac318. eCollection 2022 Jul.
2
An atypical case of necrotizing fasciitis secondary to perforated cecal cancer.一例继发于盲肠癌穿孔的坏死性筋膜炎非典型病例。
J Surg Case Rep. 2020 Nov 10;2020(11):rjaa371. doi: 10.1093/jscr/rjaa371. eCollection 2020 Nov.
3
Left lower limb fasciitis due to sigmoid colonic perforated diverticulitis: a rare case of colocutaneous fistula.
乙状结肠穿孔性憩室炎致左下肢筋膜炎:罕见的结肠皮肤瘘病例
J Surg Case Rep. 2020 Aug 31;2020(8):rjaa264. doi: 10.1093/jscr/rjaa264. eCollection 2020 Aug.
4
A rare case of multi-focal non-contiguous necrotizing soft tissue infections and literature review.一例罕见的多灶性非连续性坏死性软组织感染病例及文献综述。
J Surg Case Rep. 2019 Nov 20;2019(11):rjz338. doi: 10.1093/jscr/rjz338. eCollection 2019 Nov.
5
Necrotizing fasciitis of the thigh due to penetrated descending colon cancer: a case report.降结肠癌穿透致大腿坏死性筋膜炎:一例报告
Surg Case Rep. 2018 Nov 26;4(1):136. doi: 10.1186/s40792-018-0544-y.
6
Necrotizing fasciitis of the lower extremity caused by perforated sigmoid diverticulitis-a case report.乙状结肠憩室穿孔引起的下肢坏死性筋膜炎——病例报告
J Surg Case Rep. 2018 Aug 6;2018(8):rjy198. doi: 10.1093/jscr/rjy198. eCollection 2018 Aug.
7
Perforated caecal carcinoma masquerading as lower limb necrotising fasciitis: lessons learnt.伪装成下肢坏死性筋膜炎的盲肠穿孔癌:经验教训
BMJ Case Rep. 2018 Jun 27;2018:bcr-2017-219412. doi: 10.1136/bcr-2017-219412.
8
Necrotizing soft tissue infection of the thigh associated with retroperitoneal abscess in a patient with locally advanced ascending colon cancer: A case report.局部晚期升结肠癌患者大腿坏死性软组织感染合并腹膜后脓肿:一例报告
IDCases. 2017 Sep 9;10:112-114. doi: 10.1016/j.idcr.2017.09.002. eCollection 2017.
9
Necrotising fasciitis of the left leg caused by perforated caecal adenocarcinoma.由盲肠腺癌穿孔引起的左腿坏死性筋膜炎。
Ann R Coll Surg Engl. 2017 Nov;99(8):e223-e224. doi: 10.1308/rcsann.2017.0138. Epub 2017 Sep 15.
10
Evaluating the Laboratory Risk Indicator to Differentiate Cellulitis from Necrotizing Fasciitis in the Emergency Department.评估实验室风险指标以在急诊科区分蜂窝织炎与坏死性筋膜炎
West J Emerg Med. 2017 Jun;18(4):684-689. doi: 10.5811/westjem.2017.3.33607. Epub 2017 May 12.