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人工关节周围感染:最新进展

Periprosthetic joint infections: state-of-the-art.

作者信息

Gehrke Thorsten, Citak Mustafa, Parvizi Javad, Budhiparama Nicolaas Cyrillus, Akkaya Mustafa

机构信息

Department of Orthopaedic Surgery, Helios ENDO-Klinik, Hamburg, Germany.

Department of International Joint Center, Acibadem, Istanbul, Maslak, Turkey.

出版信息

Arch Orthop Trauma Surg. 2024 Dec 18;145(1):58. doi: 10.1007/s00402-024-05627-5.

DOI:10.1007/s00402-024-05627-5
PMID:39694911
Abstract

In general, periprosthetic joint infection (PJI) is regarded as one of the most common complications of total joint arthroplasty (TJA) and may lead to surgical failure, revision surgery, amputation or death. Nowadays, PJI has become a global health concern, which brings a great burden to public healthcare. In addition, there are still obstacles to achieve high success rates in the prevention, diagnosis and treatment of PJI. However, promising studies are also available with the advancements in biotechnology. This article will present an overview of the current methods used in the prevention, diagnosis and management of PJI while underlining the new technologies utilized.

摘要

一般来说,人工关节周围感染(PJI)被认为是全关节置换术(TJA)最常见的并发症之一,可能导致手术失败、翻修手术、截肢或死亡。如今,PJI已成为全球卫生关注的问题,给公共医疗保健带来了巨大负担。此外,在PJI的预防、诊断和治疗方面实现高成功率仍存在障碍。然而,随着生物技术的进步,也有一些很有前景的研究。本文将概述目前用于PJI预防、诊断和管理的方法,同时强调所采用的新技术。

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Periprosthetic joint infections: state-of-the-art.人工关节周围感染:最新进展
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引用本文的文献

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本文引用的文献

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Prevention of surgical site infection: a ten-step approach.手术部位感染的预防:十步法
Arthroplasty. 2023 Apr 8;5(1):21. doi: 10.1186/s42836-023-00174-7.
2
Utility of D-dimer in total joint arthroplasty.D-二聚体在全关节置换术中的应用价值。
World J Orthop. 2023 Mar 18;14(3):90-102. doi: 10.5312/wjo.v14.i3.90.
3
The combined evaluation of fibrinogen and D-dimer levels are a helpful tool to exclude periprosthetic knee infection.联合评估纤维蛋白原和 D-二聚体水平有助于排除人工膝关节感染。
J Orthop Res. 2023 Aug;41(8):1840-1847. doi: 10.1002/jor.25515. Epub 2023 Jan 16.
4
Successful eradication rate following one-stage septic knee and hip exchange in selected pre-operative culture-negative periprosthetic joint infections.一期关节感染清创联合髋关节或膝关节置换术治疗术前培养阴性的假体周围感染的成功率。
Int Orthop. 2023 Mar;47(3):659-666. doi: 10.1007/s00264-022-05677-7. Epub 2022 Dec 28.
5
Effects of different doses of vancomycin powder in total knee and hip arthroplasty on the periprosthetic joint infection rate: a systematic review and meta-analysis.不同剂量万古霉素粉末在全膝关节和髋关节置换术中对假体周围关节感染率的影响:系统评价和荟萃分析。
J Orthop Surg Res. 2022 Dec 17;17(1):546. doi: 10.1186/s13018-022-03445-2.
6
Recent advances in prevention, detection and treatment in prosthetic joint infections of bioactive materials.生物活性材料在人工关节感染预防、检测和治疗方面的最新进展。
Front Bioeng Biotechnol. 2022 Nov 10;10:1053399. doi: 10.3389/fbioe.2022.1053399. eCollection 2022.
7
Clinical and cost effectiveness of single stage compared with two stage revision for hip prosthetic joint infection (INFORM): pragmatic, parallel group, open label, randomised controlled trial.一期与二期翻修治疗髋关节假体关节感染的临床和成本效果比较(INFORM):实用、平行组、开放标签、随机对照试验。
BMJ. 2022 Oct 31;379:e071281. doi: 10.1136/bmj-2022-071281.
8
Cell-free Deoxyribonucleic Acid: A Potential Biomarker of Chronic Periprosthetic Knee Joint Infection.无细胞游离脱氧核糖核酸:慢性人工膝关节假体周围感染的潜在生物标志物。
J Arthroplasty. 2022 Dec;37(12):2455-2459. doi: 10.1016/j.arth.2022.07.002. Epub 2022 Jul 12.
9
Alpha-Defensin Offers Limited Utility in Work-Up Prior to Reimplantation in Chronic Periprosthetic Joint Infection in Total Joint Arthroplasty Patients.α-防御素在全关节置换术患者慢性人工关节周围感染再植入术前检查中的应用价值有限。
J Arthroplasty. 2022 Dec;37(12):2431-2436. doi: 10.1016/j.arth.2022.06.024. Epub 2022 Jul 5.
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Synovial C-Reactive Protein is a Useful Adjunct for Diagnosis of Periprosthetic Joint Infection.滑膜 C 反应蛋白对假体周围关节感染的诊断具有辅助作用。
J Arthroplasty. 2022 Dec;37(12):2437-2443.e1. doi: 10.1016/j.arth.2022.06.016. Epub 2022 Jun 22.