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Strategies to improve recruitment in mental health clinical trials: a scoping review (RE-MIND study).

作者信息

Iflaifel Mais, Hall Charlotte L, Green Heidi R, Willis Andrew, Rennick-Egglestone Stefan, Juszczak Edmund, Townsend Mark, Martin Jennifer, Sprange Kirsty

机构信息

Nottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK.

NIHR MindTech MedTech Co-operative, Institute of Mental Health, School of Medicine, Mental Health and Clinical Neurosciences, University of Nottingham, Innovation Park, Triumph Road, Nottingham, UK.

出版信息

Trials. 2024 Dec 18;25(1):832. doi: 10.1186/s13063-024-08665-x.


DOI:10.1186/s13063-024-08665-x
PMID:39695709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11654402/
Abstract

BACKGROUND: Lower-than-expected recruitment continues to be one of the major causes of trial delays, and trials to improve mental health are no exception. Indeed, recruitment challenges in trials of vulnerable populations, such as those living with mental health illness, can even be exacerbated. To address this, researchers are turning to digital and online recruitment strategies, e.g. web-based approaches and multi-media in order to (1) increase recruitment efficiency (recruit to target and on time) and (2) improve diversity in mental health clinical trials to be more inclusive and reduce health inequity. There is, however, inconclusive evidence on the success of digital and online recruitment strategies in mental health clinical trials. The RE-MIND study comprised a scoping review to assess the impact of using such recruitment strategies in mental health clinical trials to inform a more systematic scoping review. METHODS: A cohort of 191 recently published RCTs and randomised feasibility studies were identified from the NIHR Journals Library and top two mental health journals (based on citation metrics), Lancet Psychiatry and JAMA Psychiatry. Population characteristics including gender, ethnicity and age were summarised for inclusivity using descriptive statistics, and recruitment strategies were compared to examine differences in their success in recruiting to target. RESULTS: After screening, 97 articles were included for review. The review findings showed no evidence that offline or mixed strategies were superior for achieving recruitment targets in mental health trials. However, there was a suggestion that trials using a mixed recruitment strategy improved inclusivity and tended to recruit closer to the target. CONCLUSIONS: The key finding was that consideration should be given to a mixed methods approach to recruitment not only to enable wider and more diverse participation in mental health trials but also to realize greater efficiency.

摘要

相似文献

[1]
Strategies to improve recruitment in mental health clinical trials: a scoping review (RE-MIND study).

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本文引用的文献

[1]
Using online methods to recruit participants into mental health clinical trials: considerations and recommendations from the RE-MIND study.

Trials. 2024-9-7

[2]
Widening participation - recruitment methods in mental health randomised controlled trials: a qualitative study.

BMC Med Res Methodol. 2023-9-21

[3]
Trial Forge Guidance 3: randomised trials and how to recruit and retain individuals from ethnic minority groups-practical guidance to support better practice.

Trials. 2022-8-17

[4]
Measuring the digital divide among people with severe mental ill health using the essential digital skills framework.

Perspect Public Health. 2024-1

[5]
Use of the Internet and Digital Devices Among People With Severe Mental Ill Health During the COVID-19 Pandemic Restrictions.

Front Psychiatry. 2021-9-24

[6]
Opportunities and challenges of delivering digital clinical trials: lessons learned from a randomised controlled trial of an online behavioural intervention for children and young people.

Trials. 2020-12-9

[7]
Online Patient Recruitment in Clinical Trials: Systematic Review and Meta-Analysis.

J Med Internet Res. 2020-11-4

[8]
Implementation of internet-delivered cognitive behaviour therapy for pediatric obsessive-compulsive disorder: Lessons from clinics in Sweden, United Kingdom and Australia.

Internet Interv. 2020-1-27

[9]
Increasing Diversity in Clinical Trials: Overcoming Critical Barriers.

Curr Probl Cardiol. 2018-11-9

[10]
Using different Facebook advertisements to recruit men for an online mental health study: Engagement and selection bias.

Internet Interv. 2017-3-2

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