Chen Hung-Yu, Su Hui-Chen, Liu Chieh-Hsiu, Wu Yi-Lin, Li Chung-Yi, Hou Wen-Hsuan, Lin Chung-Ying, Yang Yi-Ching, Griffiths Mark D
Department of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Department of Neurology, National Cheng-Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
OTJR (Thorofare N J). 2025 Oct;45(4):630-639. doi: 10.1177/15394492241304323. Epub 2024 Dec 19.
Intrinsic capacity (IC), an internal composite ability proposed by the World Health Organization, is fundamental to older people's health. The present study examined potential models explaining the association between IC and quality of life (QoL) among older people in Taiwan. Frailty, basic activities of daily living (BADL), and instrumental activities of daily living (IADL) were hypothesized to be mediators in the association between IC and QoL. Older people aged 50 years or above from community or medical center ( = 1,235; = 72.63 years [ = 7.19]; 601 males [48.7%]) completed a series of self-report and functional measures assessing IC, frailty, ADLs, and QoL. Results showed that IC was significantly associated with frailty, BADL, IADL, and QoL in the mediation models. Frailty was found to be a significant mediator in the association between IC and QoL alone or together with IADL. The findings indicate that IC is an important factor for older people to maintain good health and live a fulfilling life.
内在能力（IC）是世界卫生组织提出的一种内在综合能力，对老年人的健康至关重要。本研究探讨了解释台湾老年人IC与生活质量（QoL）之间关联的潜在模型。虚弱、基本日常生活活动（BADL）和工具性日常生活活动（IADL）被假设为IC与QoL之间关联的中介因素。来自社区或医疗中心的50岁及以上老年人（n = 1235；平均年龄 = 72.63岁[标准差 = 7.19]；601名男性[48.7%]）完成了一系列自我报告和功能测量，以评估IC、虚弱、日常生活活动能力和生活质量。结果表明，在中介模型中，IC与虚弱、BADL、IADL和QoL显著相关。单独或与IADL一起，虚弱被发现是IC与QoL之间关联的一个重要中介因素。研究结果表明，IC是老年人保持良好健康和过上充实生活的重要因素。
