Castle Ellen M, Billany Roseanne E, Young Hannah M L, Walklin Christy, Briggs Juliet, Asgari Elham, Bhandari Sunil, Burton James O, Bramham Kate, Deelchand Vashist, Hamilton Alexander, Jesky Mark, Kalra Philip A, McCafferty Kieran, Nixon Andrew C, Taal Maarten W, Tollit James, Wheeler David C, Macdonald Jamie, Greenwood Sharlene A
Curtin School of Allied Health, Faculty of Health Sciences, Curtin University, Western Australia, Australia.
Physiotherapy Division, College of Health, Medicine and Life Sciences, Brunel University London, UK.
Kidney Int Rep. 2024 Oct 10;9(12):3517-3531. doi: 10.1016/j.ekir.2024.09.029. eCollection 2024 Dec.
The Kidney BEAM randomized controlled trial reported clinically meaningful and statistically significant improvements in mental health-related quality of life (HRQoL), physical function (sit-to-stand-60, but not the physical component of HRQoL) and patient activation after a 12-week physical activity digital health intervention (DHI). This study explores factors that contributed to the effectiveness of Kidney BEAM through mixed methods analyses.
Quantitative data analysis was obtained from the recently published primary manuscript. Participants from the Kidney BEAM trial intervention group ( = 30) completed individualized semistructured interviews after the 12-week DHI. Interviews were analyzed using the framework method with inductive and deductive coding. Quantitative and qualitative data collection and analyses occurred concurrently, and independently, before combining using a mixed methods analysis with joint displays to triangulate datasets and further explore the primary findings.
The integrated mixed methods analyses facilitated explanation of the primary findings. The Kidney BEAM intervention was shown to have mental and physical wellbeing benefits and enhanced self-management in this cohort of people living with chronic kidney disease (CKD). Elements that contributed to the effectiveness of the intervention were reported, including the different functional levels and gradual progression of the program, shared lived experiences with other participants, self-monitoring, the sense of achievement, taking back control of their health, moving beyond medications, and feeling safe and confident to exercise.
Elements of the Kidney BEAM intervention that contributed to the main quantitative trial findings were identified. This will allow researchers and practitioners to maximize the effectiveness of DHIs to enhance healthy behaviors in people living with CKD.
肾脏BEAM随机对照试验报告称,在进行为期12周的体育活动数字健康干预(DHI)后,与心理健康相关的生活质量(HRQoL)、身体功能(从坐到站60次,但不包括HRQoL的身体组成部分)以及患者自我管理能力在临床上有显著改善且具有统计学意义。本研究通过混合方法分析,探讨了促成肾脏BEAM干预有效性的因素。
定量数据分析取自最近发表的主要手稿。肾脏BEAM试验干预组的参与者(n = 30)在为期12周的DHI结束后完成了个体化半结构化访谈。访谈采用框架法进行分析,包括归纳编码和演绎编码。定量和定性数据的收集与分析同时且独立进行,然后使用联合展示的混合方法分析将两者结合,以对数据集进行三角验证并进一步探索主要研究结果。
综合混合方法分析有助于解释主要研究结果。肾脏BEAM干预在这一慢性肾脏病(CKD)患者队列中显示出对心理和身体健康有益,并增强了自我管理能力。报告了促成干预有效性的因素,包括项目的不同功能水平和逐步推进、与其他参与者共同的生活经历、自我监测、成就感、重新掌控自己的健康、超越药物治疗以及感到安全并有信心进行锻炼。
确定了肾脏BEAM干预中促成主要定量试验结果的因素。这将使研究人员和从业者能够最大限度地提高数字健康干预的有效性,以促进CKD患者的健康行为。