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低剂量计算机断层扫描（CT）技术用于骨性III类错牙合畸形上颌面部骨三维（3D）打印的可行性研究

Feasibility study of low-dose computed tomography (CT) technology for maxillofacial bone three-dimensional (3D) printing in skeletal class III malocclusion.

作者信息

Miao Qian, Li Guan, Wáng Yì Xiáng J, Wang Jinbao, Wang Haopeng, Chen Wei, Shao Yang

机构信息

Department of Anesthesiology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

出版信息

Quant Imaging Med Surg. 2024 Dec 5;14(12):8238-8248. doi: 10.21037/qims-22-1266. Epub 2024 Oct 17.

DOI:10.21037/qims-22-1266
PMID:39698645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11651978/
Abstract

BACKGROUND

Skeletal class III malocclusion is among the most common dental and maxillofacial malformations. Three-dimensional (3D) printing technology has become widely applied in orthopaedics. The data source for 3D printing of maxillofacial bones is computed tomography (CT). The issue of the CT radiation dose caused by maxillofacial bone 3D printing has attracted increasing attention. This study aimed to explore the feasibility of low-dose CT technology in maxillofacial bone 3D printing and the clinical value of low-dose maxillofacial bone 3D printing.

METHODS

Ninety patients with class III malocclusion who planned to undergo maxillofacial bone 3D printing and 3D-CT were prospectively enrolled and randomly divided into the conventional CT dose 3D printing group (Group A, n=28), low-CT dose 3D printing group (Group B, n=32) and 3D-CT control group (Group C, n=30). The quality of maxillofacial bone 3D printing was subjectively evaluated, and a Likert-scale questionnaire was used to assess the clinical value of maxillofacial bone 3D printing.

RESULTS

No significant differences in the general demographic characteristics were detected among Groups A, B, and C. Compared with that in Group A (0.8±0.1 mSv), the radiation effective dose (ED) in Group B (0.3±0.1 mSv) was reduced by approximately 63%. There were no significant differences between Groups A and B in 3D printing quality indices (including clarity, integrity, accuracy or artefacts) (all P>0.05). There were significantly higher subjective scores for the clinical value of maxillofacial bone 3D printing (Group A=4.1±0.5, 4.0±0.5, 4.0±0.4 and 4.1±0.5; Group B=4.0±0.5, 4.0±0.4, 4.0±0.5 and 4.0±0.5) than for 3D-CT (Group C=3.1±0.5, 3.1±0.4, 2.9±0.4 and 3.0±0.4) in diagnosing and classifying, formulating the surgical plan, simulating the surgical process, and predicting postoperative recovery (all P<0.05).

CONCLUSIONS

Low-dose CT technology can be effectively applied for maxillofacial bone 3D printing, reducing the radiation dose without affecting the 3D printing quality. Maxillofacial bone 3D printing technology is superior to 3D-CT in class III malformations.

摘要

背景

骨性III类错牙合畸形是最常见的牙颌面畸形之一。三维（3D）打印技术已在骨科中广泛应用。颌面骨3D打印的数据源是计算机断层扫描（CT）。颌面骨3D打印所引起的CT辐射剂量问题已受到越来越多的关注。本研究旨在探讨低剂量CT技术在颌面骨3D打印中的可行性以及低剂量颌面骨3D打印的临床价值。

方法

前瞻性纳入90例计划进行颌面骨3D打印及3D-CT检查的III类错牙合畸形患者，并随机分为常规CT剂量3D打印组（A组，n=28）、低CT剂量3D打印组（B组，n=32）和3D-CT对照组（C组，n=30）。对颌面骨3D打印质量进行主观评价，并采用Likert量表问卷评估颌面骨3D打印的临床价值。

结果

A、B、C三组患者的一般人口学特征无显著差异。与A组（0.8±0.1 mSv）相比，B组的辐射有效剂量（ED）（0.3±0.1 mSv）降低了约63%。A组和B组在3D打印质量指标（包括清晰度、完整性、准确性或伪影）方面无显著差异（均P>0.05）。在诊断和分类、制定手术计划、模拟手术过程以及预测术后恢复方面，颌面骨3D打印的临床价值主观评分（A组分别为4.1±0.5、4.0±0.5、4.0±0.4和4.1±0.5；B组分别为4.0±0.5、4.0±0.4、4.0±0.5和4.0±0.5）显著高于3D-CT（C组分别为3.1±0.5、3.1±0.4、2.9±0.4和3.0±0.4）（均P<0.05）。

结论

低剂量CT技术可有效应用于颌面骨3D打印，在不影响3D打印质量的同时降低辐射剂量。在III类错牙合畸形中，颌面骨3D打印技术优于3D-CT。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/5e70c6e44738/qims-14-12-8238-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/b1518ce37185/qims-14-12-8238-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/b24094f198df/qims-14-12-8238-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/ed9bb95a0b12/qims-14-12-8238-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/f3b965db8f58/qims-14-12-8238-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/8414b8466644/qims-14-12-8238-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/5e70c6e44738/qims-14-12-8238-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/b1518ce37185/qims-14-12-8238-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/b24094f198df/qims-14-12-8238-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/ed9bb95a0b12/qims-14-12-8238-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/f3b965db8f58/qims-14-12-8238-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/8414b8466644/qims-14-12-8238-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f6/11651978/5e70c6e44738/qims-14-12-8238-f6.jpg

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