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一项旨在增加黑人和非裔美国人获得活体供肾移植机会的随机试验的干预后即时结果。

Immediate Postintervention Outcomes from a Randomized Trial that Sought to Enhance Access to Live Donor Kidney Transplant for Black and African Americans.

作者信息

Arriola Kimberly Jacob, Barrett D'Jata, Pastan Stephen, Perryman Jennie, DuBay Derek, Tresslar Courtney, De Abreu Sara Useche, Di Mengyu, Teunis Larissa, Montoya Miranda, Mangurenje Tatenda, Patzer Rachel E

机构信息

Department of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

Prog Transplant. 2025 Mar;35(1):5-12. doi: 10.1177/15269248241304794. Epub 2024 Dec 19.

DOI:10.1177/15269248241304794
PMID:39698959
Abstract

INTRODUCTION

Eliminating racial inequities in access to kidney transplantation requires multilevel interventions that target both patients and health systems.

RESEARCH QUESTION

The aim of this study was to determine whether adding culturally sensitive, web-based patient education to a transplant center-level intervention was associated with increased knowledge, motivation to pursue living donor kidney transplant, and confidence in the behavioral skills to discuss living donation among Black/African American patients with end-stage kidney disease.

DESIGN

A total of 411 transplant candidates were randomized to intervention (N = 222) or control groups (N = 189) and completed measures at baseline and immediate follow-up during the transplant evaluation visit.

RESULTS

Results indicated no significant change in knowledge across time or study condition. At immediate follow-up, participants of both study conditions exhibited a significantly higher motivation to pursue living donation (t = 3.066,  < .01) versus at baseline. Both study conditions demonstrated increased confidence in the behavioral skills to discuss living donation over time (t = 3.580,  < .001). Process evaluation findings demonstrated limited engagement with the online video content across both conditions.

CONCLUSION

Results suggest that the intervention did not perform better than control but raised important considerations for the delivery of transplant education targeting Black/African American patients in a busy clinical setting.

摘要

引言

消除肾移植获取方面的种族不平等需要针对患者和卫生系统的多层次干预措施。

研究问题

本研究的目的是确定在移植中心层面的干预措施中增加具有文化敏感性的网络患者教育,是否与晚期肾病的黑人/非裔美国患者在获取活体供肾移植的知识、动机以及讨论活体捐赠行为技能的信心方面的增加有关。

设计

总共411名移植候选人被随机分为干预组(N = 222)或对照组(N = 189),并在移植评估访视期间的基线和即时随访时完成测量。

结果

结果表明,随着时间推移或研究条件的变化,知识水平没有显著变化。在即时随访时,与基线相比,两种研究条件下的参与者在寻求活体捐赠方面的动机均显著更高(t = 3.066,P <.01)。随着时间的推移,两种研究条件下的参与者在讨论活体捐赠行为技能方面的信心均有所增加(t = 3.580,P <.001)。过程评估结果表明,两种情况下对在线视频内容的参与度都有限。

结论

结果表明,该干预措施并不比对照组表现更好,但为在繁忙临床环境中针对黑人/非裔美国患者开展移植教育提出了重要的考虑因素。

相似文献

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Immediate Postintervention Outcomes from a Randomized Trial that Sought to Enhance Access to Live Donor Kidney Transplant for Black and African Americans.一项旨在增加黑人和非裔美国人获得活体供肾移植机会的随机试验的干预后即时结果。
Prog Transplant. 2025 Mar;35(1):5-12. doi: 10.1177/15269248241304794. Epub 2024 Dec 19.
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Racial differences in the living kidney donation experience and implications for education.活体肾捐献经历中的种族差异及其对教育的启示。
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Prog Transplant. 2015 Jun;25(2):164-75. doi: 10.7182/pit2015852.
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Trends in African Americans' Attitudes and Behaviors About Living Donor Kidney Transplantation.非裔美国人对活体肾移植的态度和行为趋势。
Prog Transplant. 2018 Dec;28(4):354-360. doi: 10.1177/1526924818800036. Epub 2018 Sep 19.
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Sex differences and attitudes toward living donor kidney transplantation among urban black patients on hemodialysis.血液透析的城市黑人患者中性别差异及对活体供肾移植的态度
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Protocol of a randomized controlled trial of culturally sensitive interventions to improve African Americans' and non-African Americans' early, shared, and informed consideration of live kidney transplantation: the Talking About Live Kidney Donation (TALK) Study.一项文化敏感干预措施改善非裔美国人和非非裔美国人早期共同知情考虑活体肾移植的随机对照试验方案:活体肾脏捐赠对话研究(TALK 研究)。
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Living donor transplant education for African American patients with end-stage renal disease.针对患有终末期肾病的非裔美国患者的活体供体移植教育。
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Identification of strategies to facilitate organ donation among African Americans using the nominal group technique.运用名义群体技术确定促进非裔美国人器官捐赠的策略。
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Modifiable patient characteristics and racial disparities in evaluation completion and living donor transplant.可改变的患者特征与评估完成情况和活体供者移植中的种族差异。
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Center-level factors and racial disparities in living donor kidney transplantation.中等级别因素与活体供肾移植中的种族差异。
Am J Kidney Dis. 2012 Jun;59(6):849-57. doi: 10.1053/j.ajkd.2011.12.021. Epub 2012 Feb 25.

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Perspectives of a mobile intervention for kidney transplant seekers: Post-intervention qualitative results from the KidneyTIME study.针对肾脏移植寻求者的移动干预措施展望:来自肾脏时间研究的干预后定性结果
PLoS One. 2025 May 30;20(5):e0325313. doi: 10.1371/journal.pone.0325313. eCollection 2025.
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Informing transplant candidate and donor education in living kidney donation: mapping educational needs through a rapid review.为活体肾移植候选者和供体教育提供信息:通过快速综述确定教育需求
BMC Nephrol. 2025 May 3;26(1):225. doi: 10.1186/s12882-025-04116-0.