黑人与白人患者胰腺导管腺癌的分子差异
Molecular Differences in Pancreatic Ductal Adenocarcinomas from Black versus White Patients.
作者信息
Mandal Saurabh, Teslow Emily A, Huang Minxuan, Yu Yingying, Sridhar Swathi, Crawford Howard C, Hockenberry Adam J, Stoppler Melissa C, Levin Albert M, Huang Ling
机构信息
Henry Ford Pancreatic Cancer Center, Henry Ford Health, Detroit, Michigan.
Tempus AI, Inc., Chicago, Illinois.
出版信息
Cancer Res Commun. 2025 Jan 1;5(1):128-137. doi: 10.1158/2767-9764.CRC-24-0376.
By analyzing the records of patients with pancreatic cancer in the Tempus multimodal database, we identified genomic mutations and PD-L1 overexpression occurred more frequently in Black patients compared with their White counterparts. These molecular features may contribute to racial disparities in pancreatic cancer.
通过分析Tempus多模态数据库中胰腺癌患者的记录，我们发现与白人患者相比，黑人患者的基因变异和程序性死亡受体配体1（PD-L1）过表达更为常见。这些分子特征可能导致胰腺癌的种族差异。
Zotero 插件