Mace S, Borkat G, Liebman J
Am J Dis Child. 1985 Jan;139(1):60-5. doi: 10.1001/archpedi.1985.02140030062030.
In infants and children, the effect of heart failure and/or cyanotic heart disease on the liver has not been well documented, nor has there been any comparison between the degree of liver dysfunction and hemodynamic factors. Sixty-five patients with cardiovascular abnormalities were examined. Hepatic function, as indicated by laboratory data and histologic liver studies, was compared with the following categories of cardiovascular dysfunction: hypoxemia, systemic venous congestion, and low cardiac output. If any one of these factors was present, or any combination, abnormalities of liver function were usually noted. Patients with both hypoxemia and systemic venous congestion had marked hepatic dysfunction. Those with low cardiac output had the most severe abnormalities. Serial studies indicated that liver function correlated with cardiac status.
在婴幼儿中，心力衰竭和/或紫绀型心脏病对肝脏的影响尚未得到充分记录，肝功能障碍程度与血流动力学因素之间也未进行过任何比较。对65例心血管异常患者进行了检查。根据实验室数据和肝脏组织学研究所示的肝功能，与以下几类心血管功能障碍进行了比较：低氧血症、体静脉充血和心输出量降低。如果存在这些因素中的任何一种或任何组合，通常会注意到肝功能异常。同时患有低氧血症和体静脉充血的患者有明显的肝功能障碍。心输出量降低的患者有最严重的异常。系列研究表明，肝功能与心脏状况相关。
