先天性弓形虫病：在过去15年中，3岁时的临床症状减少，但母婴传播风险稳定。
Congenital toxoplasmosis: Fewer clinical signs at 3 years of age over the last 15 years but stable risk of materno-fetal transmission.
作者信息
Wallon Martine, Ksiazek Elea, Journé Antoine, Dupont Damien, Menotti Jean, Peyron François, Binquet Christine
机构信息
Service de Parasitologie et de Mycologie Médicale, Institut des Agents Infectieux, Hospices Civils de Lyon, Lyon, France.
Walking Team, Centre for Research in Neuroscience in Lyon, Bron, France.
出版信息
Clin Infect Dis. 2024 Dec 20. doi: 10.1093/cid/ciae634.
Risk and severity of congenital toxoplasmosis were estimated using data from 2,455 consecutive mother/child pairs. Clinical signs at 3 years were halved in the 177 children born since 2009 compared to 1996-2008 (OR=0.49; 95% Confidence interval 0.28-0.85). Maternofetal transmission rates remained stable from 1992 to 2021.
利用来自2455对连续母婴的数据，对先天性弓形虫病的风险和严重程度进行了评估。与1996 - 2008年相比，2009年以来出生的177名儿童在3岁时的临床症状减少了一半（比值比=0.49；95%置信区间0.28 - 0.85）。1992年至2021年，母婴传播率保持稳定。
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