Jones C E, Jamil Y
Guy's and St Thomas' NHS Foundation Trust, London, UK.
University College London Hospital Trust, North Central London Maternal Medicine network, London, UK.
Clin Med (Lond). 2025 Jan;25(1):100277. doi: 10.1016/j.clinme.2024.100277. Epub 2024 Dec 17.
Asthma is the most common chronic disease to affect pregnant women and can have a significant effect on pregnancy outcomes, with increased rates of preterm birth, premature delivery and caesarean section observed if poorly controlled. Pregnancy can also influence asthma control. Prescribing in pregnancy causes anxiety for patients and healthcare professionals and can result in alteration or undertreatment of asthma. Good asthma control with prompt and adequate management of exacerbations is key to reducing adverse pregnancy outcomes for both mother and fetus. The majority of asthma treatment can be continued as normal in pregnancy and there is emerging evidence of the safety of biologic medications also. This article aims to summarise the current evidence about asthma in pregnancy and guide the appropriate management of this population.
哮喘是影响孕妇的最常见慢性病,对妊娠结局有重大影响。如果控制不佳,早产、早产和剖宫产率会增加。妊娠也会影响哮喘的控制。孕期用药会让患者和医护人员感到焦虑,并可能导致哮喘治疗方案改变或治疗不足。通过及时、充分地处理病情加重来实现良好的哮喘控制,是降低母婴不良妊娠结局的关键。大多数哮喘治疗药物在孕期可照常使用,而且越来越多的证据表明生物制剂也具有安全性。本文旨在总结目前关于孕期哮喘的证据,并指导对这一人群的合理管理。