Suman Saurav, Ali Hammad, Buechler Connor R, Rogers Heidi C, Roberts W Neal
Division of Rheumatology, Penn State University, Hershey, PA, USA.
Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA.
Lupus. 2025 Feb;34(2):178-180. doi: 10.1177/09612033241310071. Epub 2024 Dec 19.
To test the ability of the 2019 EULAR/ACR Classification Criteria for SLE score to predict lupus related hospitalization and overall cost of hospitalization.
217 University of Kentucky patient records that met our preliminary inclusion criteria, 44 patients were selected by a random number generator algorithm for a thorough chart review to collect data needed for calculation of the 2019 EULAR/ACR Classification Criteria for SLE score. Total hospitalization cost was calculated by using hospital adjusted expenses per inpatient day data, which estimates the expense incurred by the hospital to provide services and thus removes the variability of charges and reimbursements introduced by insurance type.
Patients with a score of 19 or more had increased risk of hospitalization in at least the 6 months after initial outpatient visit as compared to their counterparts with scores less than 19 [= .069]. The odds of being hospitalized for lupus among those with initial score ≥19 was 5.71 times higher than for those with score <19. Patients who scored 19 or less at initial visit had a mean hospitalization cost of $14,499, whereas those scored >19 had mean hospitalization cost of $28,725.
This study adds to the growing evidence that 2019 EULAR/ACR Classification Criteria score for SLE can be used as a surrogate marker to assess disease severity. The weighted 2019 EULAR/ACR Classification Criteria for SLE score offers a promising tool beyond its primary objective to find true lupus cases for research and clinical trials.
检验2019年欧洲抗风湿病联盟/美国风湿病学会（EULAR/ACR）系统性红斑狼疮（SLE）分类标准评分预测狼疮相关住院及住院总费用的能力。
217份符合我们初步纳入标准的肯塔基大学患者记录，通过随机数生成算法选取44例患者进行全面病历审查，以收集计算2019年EULAR/ACR SLE分类标准评分所需的数据。住院总费用通过使用医院调整后的每日住院费用数据进行计算，该数据估计了医院提供服务所产生的费用，从而消除了保险类型导致的收费和报销差异。
与初始门诊就诊后6个月内评分低于19分的患者相比，评分19分及以上的患者住院风险增加[=0.069]。初始评分≥19分的患者因狼疮住院的几率比评分<19分的患者高5.71倍。初始就诊时评分19分及以下的患者平均住院费用为14499美元，而评分>19分的患者平均住院费用为28725美元。
本研究进一步证明，2019年EULAR/ACR SLE分类标准评分可作为评估疾病严重程度的替代指标。加权后的2019年EULAR/ACR SLE分类标准评分除了其寻找真正狼疮病例用于研究和临床试验的主要目标外，还提供了一个有前景的工具。
