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活体肝供者的生活体验:定性研究的元综合分析

The lived experience of living liver donors: A meta-synthesis of qualitative studies.

作者信息

Dong Li, Li Zhiru, Lv Feicui, Zheng Li, Lu Fangyan

机构信息

Department of Nursing, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

School of Nursing, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

BMC Nurs. 2024 Dec 19;23(1):925. doi: 10.1186/s12912-024-02611-7.

DOI:10.1186/s12912-024-02611-7
PMID:39702105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11657966/
Abstract

BACKGROUND

Living liver donors are frequently used for liver transplantation, but they experience many physical changes and psychological challenges. A better understanding of the experiences of liver donors can provide them with comprehensive and individualized patient-centred support and health care. Thus, this study sought to identify and synthesize existing qualitative studies to develop an in-depth understanding of the lived experiences of living liver donors.

METHOD

A meta-synthesis was conducted and reported in accordance with the Enhancing Transparency in Reporting the Synthesis of Qualitative Research statement. Seven databases were systematically searched from inception to March, 2024, using a combination of Medical Subject Headings with keywords. The results were integrated using the three-step thematic synthesis method suggested by Thomas and Harden.

RESULTS

Nine studies met the inclusion criteria and were included in this meta-synthesis. Four themes emerged from the meta-synthesis: (1) facing a life-changing situation, (2) experiencing changes in interpersonal relationships, (3) coping with changes, and (4) achieving personal growth.

CONCLUSIONS

Living liver donors experienced physical, psychological, and social changes after surgery, striving to manage these challenges, highlighting the importance of coping strategies and ultimately achieving personal growth. Future nursing research should focus on psychological interventions, supportive measures, and the positive aspects of living liver donors to help them achieve the optimal quality of life.

TRIAL REGISTRATION

PROSPERO CRD42022328947.

摘要

背景

活体肝供体常用于肝移植,但他们会经历许多身体变化和心理挑战。更好地了解肝供体的经历可为他们提供全面且个性化的以患者为中心的支持与医疗服务。因此,本研究旨在识别并综合现有定性研究,以深入了解活体肝供体的生活经历。

方法

按照《提高定性研究综合报告的透明度》声明进行并报告了一项元综合分析。从数据库建库至2024年3月,使用医学主题词与关键词相结合的方式对七个数据库进行了系统检索。结果采用托马斯和哈登建议的三步主题综合法进行整合。

结果

九项研究符合纳入标准并被纳入本元综合分析。元综合分析得出了四个主题:(1)面临改变生活的状况,(2)经历人际关系的变化,(3)应对变化,以及(4)实现个人成长。

结论

活体肝供体术后经历了身体、心理和社会方面的变化,努力应对这些挑战,凸显了应对策略的重要性,并最终实现了个人成长。未来的护理研究应关注心理干预、支持措施以及活体肝供体的积极方面,以帮助他们实现最佳生活质量。

试验注册

PROSPERO CRD42022328947。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdc2/11657966/d5bc6b4577fe/12912_2024_2611_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdc2/11657966/eea579356b08/12912_2024_2611_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdc2/11657966/d5bc6b4577fe/12912_2024_2611_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdc2/11657966/eea579356b08/12912_2024_2611_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdc2/11657966/d5bc6b4577fe/12912_2024_2611_Fig2_HTML.jpg

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本文引用的文献

1
Living Kidney Donation: A Narrative Review of Mid- and Long-term Psychosocial Outcomes.活体肾捐赠:对中长期心理社会结局的叙述性综述
Transplantation. 2025 Feb 1;109(2):259-272. doi: 10.1097/TP.0000000000005094. Epub 2024 Jun 18.
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Financial toxicity in living donor liver transplantation: A call to action for financial neutrality.活体肝移植中的财务毒性:呼吁财务中立。
Am J Transplant. 2024 Oct;24(10):1742-1754. doi: 10.1016/j.ajt.2024.05.012. Epub 2024 May 18.
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Psychological Impact of Living Kidney Donation: A Systematic Review by the EAU-YAU Kidney Transplant Working Group.
活体肾脏捐赠的心理影响:EAU-YAU 肾脏移植工作组的系统评价。
Transpl Int. 2023 Nov 24;36:11827. doi: 10.3389/ti.2023.11827. eCollection 2023.
4
OPTN/SRTR 2021 Annual Data Report: Liver.OPTN/SRTR 2021 年度数据报告:肝脏。
Am J Transplant. 2023 Feb;23(2 Suppl 1):S178-S263. doi: 10.1016/j.ajt.2023.02.006.
5
Liver Transplantation 2023: Status Report, Current and Future Challenges.肝脏移植 2023:现状报告、当前和未来的挑战。
Clin Gastroenterol Hepatol. 2023 Jul;21(8):2150-2166. doi: 10.1016/j.cgh.2023.04.005. Epub 2023 Apr 20.
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A qualitative systematic review of anonymous/unspecified living kidney and liver donors' perspectives.匿名/未指定活体肾和肝供体观点的定性系统评价
PLoS One. 2022 Dec 30;17(12):e0277792. doi: 10.1371/journal.pone.0277792. eCollection 2022.
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Experiences of physical complications and sequelae among living liver donors.活体肝供者身体并发症及后遗症的经历。
Korean J Transplant. 2019 Jun 30;33(2):36-45. doi: 10.4285/jkstn.2019.33.2.36.
8
Evaluation of Psychosocial Outcomes of Living Liver Donors in Liver Transplantation.肝移植中活体肝供者的心理社会结局评估。
Turk J Gastroenterol. 2022 Apr;33(4):346-355. doi: 10.5152/tjg.2022.21262.
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Perioperative management of living donor liver transplantation: Part 2 - Donors.活体肝移植的围手术期管理:第 2 部分 - 供体。
Clin Transplant. 2022 Jun;36(6):e14690. doi: 10.1111/ctr.14690. Epub 2022 May 3.
10
Perioperative management of adult living donor liver transplantation: Part 1 - recipients.成人活体供肝肝移植的围手术期管理:第 1 部分 - 受者。
Clin Transplant. 2022 Jun;36(6):e14667. doi: 10.1111/ctr.14667. Epub 2022 Apr 24.