Braff D L, Saccuzzo D P
Am J Psychiatry. 1985 Feb;142(2):170-4. doi: 10.1176/ajp.142.2.170.
A visual backward masking task was used to specify the time course of the information-processing dysfunction in 19 schizophrenic patients and 15 matched control patients using novel interstimulus intervals. The authors found that the information-processing deficit in schizophrenic subjects occurred at interstimulus intervals of greater than 60 msec and less than 500 msec. These data are compared with the results of evoked-potential and other psychophysiological studies. The visual-processing impairment is specific and time-linked rather than a reflection of the effects of gross psychopathology or medication in schizophrenic individuals.
采用视觉逆向掩蔽任务，通过新颖的刺激间隔时间，来明确19例精神分裂症患者及15例匹配的对照患者信息处理功能障碍的时间进程。作者发现，精神分裂症患者的信息处理缺陷出现在刺激间隔时间大于60毫秒且小于500毫秒时。这些数据与诱发电位及其他心理生理学研究结果进行了比较。视觉处理损害具有特异性且与时间相关，而非精神分裂症个体严重精神病理学或药物影响的反映。
