Nowaczyk Anna, Cwajda-Białasik Justyna, Szewczyk Maria T
Department of Cardiac Rehabilitation and Health Promotion, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Department of Perioperative Nursing, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.
Med Sci Monit. 2024 Dec 20;30:e946793. doi: 10.12659/MSM.946793.
This study included 107 patients with peripheral arterial disease (PAD) undergoing revascularization and aimed to evaluate the effects of body mass index (BMI) on outcomes of quality of life (intermittent claudication questionnaire - ICQ), pain-free walking distance (PFWD), and maximum claudication distance (MCD). The study included 107 patients aged 18-80 years with PAD undergoing revascularization (average age 66±6.7 years; 82% men and 18% women, average BMI 28.02±4.35). The diagnosis of PAD was made based on medical opinion and an ankle-brachial index (ABI) value of <0.9. Methods used were BMI assessment, PFWD and MCD distances assessment (treadmill test using the Gardner-Skinner protocol), and quality of life assessment (ICQ). The examination was performed twice - at 1-5 days before the planned revascularization (classical surgery, angioplasty, or hybrid) and 3 months after the procedure. A statistically significant correlation was demonstrated between the improvement of PFWD, MCD, ICQ, and patients' BMI (P<0.01). The worst results were achieved by patients with II-degree obesity (PFWD improvement by an average 10.33±0.87, MCD of 21.67±3.25, ICQ of 14.01±0.60), while the best results were obtained by those with normal body weight (PFWD improvement by an average of 52.57±2.42, MCD of 137.20±22.30, ICQ of 21.18±0.54). Patients with a higher BMI have worse PFWD and MCD distances and quality of life 3 months after revascularization, which indicates the need to consider obesity when planning therapy. Further studies are needed to better understand the impact of BMI on the effectiveness of treatment and rehabilitation of patients with PAD.
本研究纳入了107例接受血运重建术的外周动脉疾病（PAD）患者，旨在评估体重指数（BMI）对生活质量结果（间歇性跛行问卷 - ICQ）、无痛步行距离（PFWD）和最大跛行距离（MCD）的影响。该研究纳入了107例年龄在18至80岁之间、接受血运重建术的PAD患者（平均年龄66±6.7岁；男性占82%，女性占18%，平均BMI为28.02±4.35）。PAD的诊断基于医学意见和踝臂指数（ABI）值<0.9。所采用的方法包括BMI评估、PFWD和MCD距离评估（使用加德纳 - 斯金纳方案进行跑步机测试）以及生活质量评估（ICQ）。检查在计划进行血运重建术（经典手术、血管成形术或杂交手术）前1至5天以及术后3个月进行了两次。PFWD、MCD、ICQ的改善与患者的BMI之间存在统计学显著相关性（P<0.01）。II度肥胖患者的结果最差（PFWD平均改善10.33±0.87，MCD为21.67±3.25，ICQ为14.01±0.60），而体重正常者的结果最佳（PFWD平均改善52.57±2.42，MCD为137.20±22.30，ICQ为21.18±0.54）。BMI较高的患者在血运重建术后3个月的PFWD和MCD距离以及生活质量较差，这表明在规划治疗时需要考虑肥胖因素。需要进一步研究以更好地了解BMI对PAD患者治疗和康复效果的影响。
