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对排卵周期缺乏了解会导致原发性不孕吗?来自部分南亚国家的证据。

Can a lack of knowledge of the ovulatory cycle result in primary infertility? Evidence from selected South Asian countries.

作者信息

Ojah Pratyashee, Pradhan Manas Ranjan

机构信息

Department of Fertility and Social Demography, International Institute for Population Sciences, Mumbai, India.

出版信息

Hum Fertil (Camb). 2025 Dec;28(1):2441832. doi: 10.1080/14647273.2024.2441832. Epub 2024 Dec 19.

DOI:10.1080/14647273.2024.2441832
PMID:39703039
Abstract

Knowledge of ovulatory cycle (KOC) is a crucial factor for successful conception. Despite sizable number of women suffering from infertility, empirical evidence on the relation between infertility and KOC is rare in South Asia. This study assesses the association between primary infertility and KOC. The data of ever-married women aged 20-49 gathered in the recent rounds of Demographic and Health Survey (DHS) for India (2019-2021), Bangladesh (2017-2018), Pakistan (2017-2018) and Nepal (2022) were analyzed. Bivariate analysis and binary logistic regression were conducted through Stata (V.17) with a 5% significance level. Women with no KOC in India [AOR:1.71, C.I.: (1.54, 1.9)] and Bangladesh [AOR:2.6, C.I.: (1.67, 4.06)] had higher odds of primary infertility than their counterparts with correct KOC. The study concludes that correct KOC is a significant predictor of primary infertility in India and Bangladesh and is insignificant in Pakistan and Nepal. Moreover, higher age at marriage and no-visit to healthcare facility were the other significant predictors of primary infertility in all four countries. Women who are struggling to conceive would benefit from education related to the timing and identification of the fertile window, which may be provided through primary healthcare providers.

摘要

了解排卵周期(KOC)是成功受孕的关键因素。尽管有相当数量的女性患有不孕症,但在南亚,关于不孕症与排卵周期之间关系的实证证据却很少。本研究评估了原发性不孕症与排卵周期之间的关联。分析了在印度(2019 - 2021年)、孟加拉国(2017 - 2018年)、巴基斯坦(2017 - 2018年)和尼泊尔(2022年)最近几轮人口与健康调查(DHS)中收集的20 - 49岁已婚女性的数据。通过Stata(V.17)进行双变量分析和二元逻辑回归,显著性水平为5%。在印度 [调整后比值比(AOR):1.71,置信区间(C.I.):(1.54,1.9)] 和孟加拉国 [AOR:2.6,C.I.:(1.67,4.06)],不了解排卵周期的女性患原发性不孕症的几率高于了解排卵周期的女性。研究得出结论,在印度和孟加拉国,正确了解排卵周期是原发性不孕症的重要预测因素,而在巴基斯坦和尼泊尔则不显著。此外,在所有四个国家,较高的结婚年龄和未就医也是原发性不孕症的其他重要预测因素。难以受孕的女性将受益于与排卵期和易受孕窗口识别相关的教育,这些教育可由初级医疗保健提供者提供。

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