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利用图像引导放疗的锥形束计算机断层扫描图像创建剂量分布后，采用容积调强弧形治疗重新计划对大型非小细胞肺癌进行离线自适应放疗。

Offline Adaptive Radiotherapy for Large Non-small Cell Lung Cancer With Volumetric Modulated Arc Therapy Replanning After Creation of Dose Distribution Using Cone-Beam Computed Tomographic Images of Image-Guided Radiotherapy.

作者信息

Ohguri Takayuki, Shiba Eiji, Kuroki Ryohei, Matsukawa Hideaki, Tani Subaru, Iwai Yoshio

机构信息

Therapeutic Radiology, University Hospital of Occupational and Environmental Health, Kitakyushu, JPN.

Radiology, University Hospital of Occupational and Environmental Health, Kitakyushu, JPN.

出版信息

Cureus. 2024 Nov 18;16(11):e73934. doi: 10.7759/cureus.73934. eCollection 2024 Nov.

DOI:10.7759/cureus.73934
PMID:39703263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11657301/
Abstract

There is a paucity of studies reporting the use of automated contouring function on cone-beam computed tomography (CBCT) images acquired during image-guided radiotherapy (IGRT) with offline adaptive radiotherapy for locally advanced non-small cell lung cancer (NSCLC). This case report discusses the use of an automated contouring function on CBCT images acquired during IGRT to quantify the dose distribution variations associated with tumor shrinkage in a patient with large NSCLC. A 72-year-old woman with locally advanced squamous cell carcinoma of the lung (T4N1M0; tumor diameter: 14 cm) underwent chemoradiotherapy. Two offline adaptive radiotherapy sessions were performed, resulting in no evidence of recurrence or distant metastasis, as well as no side effects of Grade 2 or higher toxicity.

摘要

关于在图像引导放射治疗（IGRT）期间获取的锥束计算机断层扫描（CBCT）图像上使用自动轮廓勾画功能，用于局部晚期非小细胞肺癌（NSCLC）的离线自适应放射治疗的研究很少。本病例报告讨论了在IGRT期间获取的CBCT图像上使用自动轮廓勾画功能，以量化一名患有大体积NSCLC患者中与肿瘤缩小相关的剂量分布变化。一名72岁患有局部晚期肺鳞状细胞癌（T4N1M0；肿瘤直径：14厘米）的女性接受了放化疗。进行了两次离线自适应放射治疗疗程，结果未发现复发或远处转移迹象，也没有2级或更高毒性的副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/10a3cb1d011b/cureus-0016-00000073934-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/ce2e5faf42b4/cureus-0016-00000073934-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/b0a66b337287/cureus-0016-00000073934-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/e2e6fbc24a79/cureus-0016-00000073934-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/10a3cb1d011b/cureus-0016-00000073934-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/ce2e5faf42b4/cureus-0016-00000073934-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/b0a66b337287/cureus-0016-00000073934-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/e2e6fbc24a79/cureus-0016-00000073934-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4b/11657301/10a3cb1d011b/cureus-0016-00000073934-i04.jpg

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本文引用的文献

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EClinicalMedicine. 2023 Sep 25;64:102246. doi: 10.1016/j.eclinm.2023.102246. eCollection 2023 Oct.
2
Coronary Artery Calcifications and Cardiac Risk After Radiation Therapy for Stage III Lung Cancer.肺癌 III 期放疗后冠状动脉钙化与心脏风险
Int J Radiat Oncol Biol Phys. 2022 Jan 1;112(1):188-196. doi: 10.1016/j.ijrobp.2021.08.017. Epub 2021 Aug 19.
3
Intensity-modulated radiation therapy with concurrent chemotherapy followed by durvalumab for stage III non-small cell lung cancer: A multi-center retrospective study.
同步化疗后使用度伐利尤单抗的调强放射治疗用于 III 期非小细胞肺癌：一项多中心回顾性研究。
Radiother Oncol. 2021 Jul;160:266-272. doi: 10.1016/j.radonc.2021.05.016. Epub 2021 May 21.
4
Cone-Beam-CT Guided Adaptive Radiotherapy for Locally Advanced Non-small Cell Lung Cancer Enables Quality Assurance and Superior Sparing of Healthy Lung.锥形束CT引导的适形放疗用于局部晚期非小细胞肺癌可实现质量保证并更好地保护健康肺组织。
Front Oncol. 2020 Dec 9;10:564857. doi: 10.3389/fonc.2020.564857. eCollection 2020.
5
Concurrent Chemo-Proton Therapy Using Adaptive Planning for Unresectable Stage 3 Non-Small Cell Lung Cancer: A Phase 2 Study.同期适形调强质子治疗不可切除 III 期非小细胞肺癌：一项 2 期研究。
Int J Radiat Oncol Biol Phys. 2021 Apr 1;109(5):1359-1367. doi: 10.1016/j.ijrobp.2020.11.035. Epub 2020 Nov 21.
6
Radiation pneumonitis in lung cancer treated with volumetric modulated arc therapy.容积调强弧形放疗治疗肺癌时的放射性肺炎
J Thorac Dis. 2018 Dec;10(12):6531-6539. doi: 10.21037/jtd.2018.11.132.
7
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J Thorac Oncol. 2017 Dec;12(12):1779-1787. doi: 10.1016/j.jtho.2017.08.010. Epub 2017 Aug 24.
8
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J Thorac Oncol. 2017 Feb;12(2):293-301. doi: 10.1016/j.jtho.2016.09.134. Epub 2016 Oct 12.
9
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Acta Oncol. 2015;54(9):1430-7. doi: 10.3109/0284186X.2015.1062544. Epub 2015 Jul 24.
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Acta Oncol. 2013 Oct;52(7):1490-6. doi: 10.3109/0284186X.2013.815798. Epub 2013 Aug 2.