Kitta Ayana, Saisu Takashi, Kakizaki Jun, Oikawa Yasuhiro, Metoki Yukie, Okazaki Ken
Department of Orthopaedics, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, JPN.
Department of Orthopaedics, Chiba Child and Adult Orthopaedic Clinic, Chiba, JPN.
Cureus. 2024 Nov 19;16(11):e74031. doi: 10.7759/cureus.74031. eCollection 2024 Nov.
Few neonatal cases of soft tissue and osteoarticular infections with have been reported. We report a rare clinical presentation of necrotizing fasciitis of the foot caused by in a 17-day-old male neonate with hypoplastic left-sided heart syndrome. Fulminant progressive black skin necrosis was triggered by fresh frozen plasma leakage from the peripheral venous access. This patient was treated with antibacterial agents as soon as skin lesions appeared, and the necrotic tissue was debrided in 48 hours. The patient recovered after three months of hospitalization without any subsequent complications in the 3.5 years of follow-up. The immune system is not fully developed at birth, resulting in high susceptibility of neonates to systemic infection. When a neonate presents with a rapidly progressive necrotizing soft tissue infection, should be considered as the possible cause and treated promptly.
很少有关于软组织和骨关节炎感染的新生儿病例报道。我们报告了一例罕见的临床病例,一名患有左心发育不全综合征的17日龄男婴,足部发生由[具体病菌未提及]引起的坏死性筋膜炎。外周静脉通路新鲜冰冻血浆渗漏引发了暴发性进行性皮肤坏死。皮肤病变出现后立即给予该患者抗菌药物治疗,并在48小时内对坏死组织进行清创。患者住院三个月后康复,在3.5年的随访中未出现任何后续并发症。新生儿出生时免疫系统尚未完全发育,导致其对全身感染高度易感。当新生儿出现快速进展的坏死性软组织感染时,应考虑[具体病菌未提及]为可能病因并及时治疗。