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急性淋巴细胞白血病的皮肤表现

Cutaneous Manifestation of Acute Lymphoblastic Leukemia.

作者信息

Cerqueira Paula, Pereira Sara, Costa Raquel, Garrido Gomes Ana

机构信息

Internal Medicine, Unidade Local de Saúde do Alto Minho - Hospital Conde de Bertiandos, Ponte de Lima, PRT.

Internal Medicine, Hospital Distrital de Santarém, Santarém, PRT.

出版信息

Cureus. 2024 Nov 19;16(11):e74022. doi: 10.7759/cureus.74022. eCollection 2024 Nov.

Abstract

Acute lymphoblastic leukemia (ALL) is a hematological neoplasm characterized by the proliferation of immature lymphoblasts. Although it is more common in children, it can also occur in adults, presenting significant clinical challenges. This case describes a 46-year-old male patient with a history of hypertension and dyslipidemia, whose first clinical manifestation of ALL was cutaneous. The patient showed resistance to initial chemotherapy, leading to complex management and, unfortunately, to a bad outcome.

摘要

急性淋巴细胞白血病(ALL)是一种血液系统肿瘤,其特征为未成熟淋巴细胞的增殖。尽管它在儿童中更为常见,但也可发生于成人,带来重大的临床挑战。本病例描述了一名46岁男性患者,有高血压和血脂异常病史,其ALL的首发临床表现为皮肤表现。该患者对初始化疗耐药,导致治疗管理复杂,不幸的是,预后不良。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8292/11658901/c84062cdc238/cureus-0016-00000074022-i01.jpg

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