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吸烟与新型冠状病毒2型感染的关联

The Association of Smoking and SARS-CoV-2 Infection.

作者信息

Sharifi Hooman, Fakharian Atefeh, Mirenayat Maryam Sadat, Moradian Gordafarid, Karimzade Saba, Tuyserkani Pouria, Zahiri Reyhaneh, Akhtari Maryam, Rekabi Mahsa, Nikpey Nafiseh, Jamaati Hamidreza

机构信息

Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Chronic Respiratory Diseases Research Center (CRDRC), NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Tanaffos. 2024 Jan;23(1):83-89.


DOI:
PMID:39703442
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11655012/
Abstract

BACKGROUND: SARS-CoV-2 is a member of the coronavirus family that has caused infections in humans. Iran, as one of the countries in West Asia, is facing a high prevalence of this virus. In this study, we aimed to investigate the association between smoking and COVID-19 outcomes during the pandemic and sociodemographic characteristics. MATERIALS AND METHODS: This cross-sectional survey was done to assess the frequency of tobacco smoking in COVID-19 patients hospitalized at Masih Daneshvari Hospital, Tehran, Iran. All patients' basic and clinical characteristics, smoking status, and outcomes (ICU admission) were recorded. RESULTS: A total of 254 participants, of whom 206 (81.10%) provided complete data on variables included in the present analyses. In the present study, 137 (66.5%) of all patients were men and 69 (33.5%) were women. Also, 63 (30.4%) of the study population had a family member with a current disease or history of COVID-19. Fourteen patients (6.79%) were ex-smokers and 34 (16.50%) were current smokers. We found significant relationships between Ex-smoking and ICU admission in COVID-19 patients. CONCLUSION: Ex-smoker inpatients with COVID-19 require special attention since they are a vulnerable population with a much higher morbidity rate.

摘要

背景:严重急性呼吸综合征冠状病毒2(SARS-CoV-2)是冠状病毒家族的一员,可导致人类感染。伊朗作为西亚国家之一,正面临该病毒的高流行率。在本研究中,我们旨在调查大流行期间吸烟与新冠肺炎结局以及社会人口学特征之间的关联。 材料与方法:本横断面调查旨在评估伊朗德黑兰马西赫·丹什瓦里医院收治的新冠肺炎患者中吸烟的频率。记录了所有患者的基本和临床特征、吸烟状况及结局(入住重症监护病房)。 结果:共有254名参与者,其中206名(81.10%)提供了本分析中所包含变量的完整数据。在本研究中,所有患者中有137名(66.5%)为男性,69名(33.5%)为女性。此外,研究人群中有63名(30.4%)有家庭成员患有新冠肺炎或有新冠肺炎病史。14名患者(6.79%)为既往吸烟者,34名(16.50%)为当前吸烟者。我们发现新冠肺炎患者中既往吸烟与入住重症监护病房之间存在显著关联。 结论:新冠肺炎住院的既往吸烟者需要特别关注,因为他们是发病率高得多的弱势群体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61e3/11655012/3500eb990b5b/Tanaffos-23-83-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61e3/11655012/5b98a968301c/Tanaffos-23-83-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61e3/11655012/e7d4d303950a/Tanaffos-23-83-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61e3/11655012/3500eb990b5b/Tanaffos-23-83-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61e3/11655012/5b98a968301c/Tanaffos-23-83-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61e3/11655012/e7d4d303950a/Tanaffos-23-83-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61e3/11655012/3500eb990b5b/Tanaffos-23-83-g003.jpg

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本文引用的文献

[1]
Lower Rate of Daily Smokers With Symptomatic COVID-19: A Monocentric Self-Report of Smoking Habit Study.

Front Med (Lausanne). 2022-1-5

[2]
Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways.

Allergy. 2022-2

[3]
The association of smoking status with SARS-CoV-2 infection, hospitalization and mortality from COVID-19: a living rapid evidence review with Bayesian meta-analyses (version 7).

Addiction. 2021-6

[4]
Corticosteroids, COVID-19 pneumonia, and acute respiratory distress syndrome.

J Clin Invest. 2020-12-1

[5]
Bariatric Surgery During the COVID-19 Pandemic-the Perspective of Physicians and Patients.

Obes Surg. 2021-3

[6]
The effect of smoking on COVID-19 severity: A systematic review and meta-analysis.

J Med Virol. 2021-2

[7]
Tobacco Smoking a Potential Risk Factor in Transmission of COVID-19 Infection.

Pak J Med Sci. 2020-5

[8]
SARS-CoV-2 COVID-19 susceptibility and lung inflammatory storm by smoking and vaping.

J Inflamm (Lond). 2020-6-10

[9]
The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system.

Cytokine Growth Factor Rev. 2020-5-11

[10]
Tobacco smoking and COVID-19 pandemic: old and new issues. A summary of the evidence from the scientific literature.

Acta Biomed. 2020-5-11

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