Machado Alejandra, Pettersson Emma, Alexanderson Kristina, Hillert Jan, Friberg Emilie
Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Division of Neurology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Mult Scler J Exp Transl Clin. 2024 Dec 18;10(4):20552173241305982. doi: 10.1177/20552173241305982. eCollection 2024 Oct-Dec.
The prodromal features of multiple sclerosis (MS) are non-specific and are prevalent in the general population. Several studies indicate an increased use of healthcare resources by individuals with MS in the years preceding their diagnosis, suggesting a trend of deteriorating health prior to the clinical manifestation of MS. This study aimed to capture the possible associations of sick leave with the timing of the diagnosis of MS. Our findings suggest that sick leave with neurological diagnoses - excluding MS, and other diagnoses during the year before MS onset is associated with a shorter time to MS diagnosis.
多发性硬化症(MS)的前驱特征不具有特异性,在普通人群中很常见。多项研究表明,MS患者在确诊前几年对医疗资源的使用有所增加,这表明在MS临床表现之前健康状况有恶化的趋势。本研究旨在找出病假与MS诊断时间之间可能存在的关联。我们的研究结果表明,患有神经疾病诊断(不包括MS)以及在MS发病前一年的其他诊断的病假与MS诊断时间较短有关。