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一名14岁免疫功能正常男孩的多发性原发性脑脓肿:来自巴基斯坦的奇异变形杆菌感染病例

Multiple primary brain abscesses in a 14 years old immunocompetent boy: A tale of Proteus mirabilis infestation from Pakistan.

作者信息

Khokhar Tariq Imran, Qadri Haseeb Mehmood, Fatima Ibreeza, Ghafoor Abdul, Bilal Muhammad Talha

机构信息

Tariq Imran Khokhar, Associate Professor, Department of Neurosurgery, Unit-I, Punjab Institute of Neurosciences, Lahore, Pakistan.

Haseeb Mehmood Qadri, Post Graduate Resident, Department of Neurosurgery, Unit-I, Punjab Institute of Neurosciences, Lahore, Pakistan.

出版信息

Pak J Med Sci. 2024 Dec;40(12PINS Suppl):S87-S89. doi: 10.12669/pjms.40.12(PINS).11033.

DOI:10.12669/pjms.40.12(PINS).11033
PMID:39703963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11654649/
Abstract

Brain abscess (BA) formation that may be due to due to Gram-positive bacteria commonly and less commonly due Gram-negative bacteria affects pediatric population. Most cases are secondary to the involvement of ear, nose, throat and sinuses (ENTS). We describe a rare case of a 14 year old patient presenting with generalized tonic clonic seizures for the last six months associated with fever, vomiting and headache. ENTS examination was normal. Neuroimaging was suggestive of multiple left fronto-pariettal space occupying lesions. Modified pterional craniotomy was done to excise the multiloculated, encapsulated lesion with yellow-green pus. Culture sensitivity yielded . Patient was discharged from the hospital uneventfully. The diagnosis of multiple primary brain abscesses secondary to is very rare and it should be considered in the list of differentials of multiple brain abscesses when the systematic examination is normal. Early surgical excision is the key to a successful outcome.

摘要

脑脓肿(BA)的形成通常由革兰氏阳性菌引起,较少由革兰氏阴性菌引起,这会影响儿童群体。大多数病例继发于耳、鼻、喉和鼻窦(ENTS)的病变。我们描述了一例罕见病例,一名14岁患者在过去六个月中出现全身性强直阵挛性癫痫发作,伴有发热、呕吐和头痛。耳鼻喉检查正常。神经影像学提示左侧额顶叶有多个占位性病变。进行了改良翼点开颅术以切除有多个分隔、包膜包裹且含有黄绿色脓液的病变。培养敏感性结果为……患者顺利出院。继发于……的多发性原发性脑脓肿的诊断非常罕见,当系统检查正常时,在多发性脑脓肿的鉴别诊断中应考虑到这一点。早期手术切除是成功治疗的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b2/11654649/25094fd595d7/PJMS-40-S87-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b2/11654649/8223c430e6ee/PJMS-40-S87-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b2/11654649/25094fd595d7/PJMS-40-S87-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b2/11654649/8223c430e6ee/PJMS-40-S87-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b2/11654649/25094fd595d7/PJMS-40-S87-g002.jpg

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Multiple primary brain abscesses in a 14 years old immunocompetent boy: A tale of Proteus mirabilis infestation from Pakistan.一名14岁免疫功能正常男孩的多发性原发性脑脓肿:来自巴基斯坦的奇异变形杆菌感染病例
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Pediatric brain abscess - etiology, management challenges and outcome in Lagos Nigeria.尼日利亚拉各斯的小儿脑脓肿——病因、管理挑战及预后
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Clinical Profile and Outcome of Brain Abscess in Children from a Tertiary Care Hospital in Eastern Uttar Pradesh.
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Ann Indian Acad Neurol. 2020 May-Jun;23(3):303-307. doi: 10.4103/aian.AIAN_425_19. Epub 2020 Jun 10.
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Brain abscess in pediatric age: a review.儿童期脑脓肿:综述
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