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[已撤回] 雌激素受体上调通过调节PI3K/AKT/mTOR通路介导子宫内膜癌细胞的迁移、侵袭和增殖。

[Retracted] Upregulation of estrogen receptor mediates migration, invasion and proliferation of endometrial carcinoma cells by regulating the PI3K/AKT/mTOR pathway.

作者信息

Hou Xinxin, Zhao Meng, Wang Tong, Zhang Guiyu

机构信息

Department of Gynecology, Qilu Hospital, Shandong University, Jinan, Shandong 250012, P.R. China.

Department of Neurosurgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China.

出版信息

Oncol Rep. 2025 Feb;53(2). doi: 10.3892/or.2024.8856. Epub 2024 Dec 20.

DOI:10.3892/or.2024.8856
PMID:39704254
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11667208/
Abstract

Following the publication of the above article, a concerned reader drew to the Editor's attention that a couple of the figures in this paper contained overlapping sections, where data which were intended to show the results from differently performed experiments had been derived from the same original source. First, regarding the cell transfection experiments in Fig. 1, the Con, ERα and ERβ data panels in Fig. 1A all contained overlapping sections of data; secondly, comparing the data panels for the cell migration and invasion assays shown in Fig. 5, three pairs of panels were also found to contain overlapping data. In view of the fact that these identifications were made in terms of overlapping data panels, the Editor of has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 31: 1175‑1182, 2014; DOI: 10.3892/or.2013.2944].

摘要

上述文章发表后,一位关注此事的读者提请编辑注意,该论文中的几幅图包含重叠部分,本应展示不同实验结果的数据却源自同一原始来源。首先,关于图1中的细胞转染实验,图1A中的对照(Con)、雌激素受体α(ERα)和雌激素受体β(ERβ)数据组均包含重叠的数据部分;其次,比较图5所示的细胞迁移和侵袭实验的数据组,也发现有三对数据组包含重叠数据。鉴于这些问题是根据重叠的数据组识别出来的, 编辑决定,由于对所呈现的数据缺乏信心,应从本刊撤回该论文。已要求作者对这些问题作出解释,但编辑部未收到令人满意的答复。编辑就由此造成的不便向读者致歉。[《肿瘤学报道》31: 1175 - 1182, 2014; DOI: 10.3892/or.2013.2944]

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